Search for dissertations about: "örebro medical"
Showing result 1 - 5 of 401 swedish dissertations containing the words örebro medical.
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1. Bioinformatics tools for discovery and evaluation of biomarkers : Applications in clinical assessment of cancer
Abstract : Cancer is a disease characterized by abnormal proliferation of cells in the body and ranks as the second leading cause of death worldwide. In order to improve cancer patient care, a major focus of cancer research is to discover biomarkers. READ MORE
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2. The molecular mechanisms behind perception and signal transduction of UV-B irradiation in Arabidopsis thaliana
Abstract : Elevation of UV-B radiation (280-315 nm), occurring as a result of depletion of the stratospheric ozone, causes a number of physiological and biochemical changes in plants. Damage to the photosynthetic apparatus (including the bleaching of the pigments which trap the sun's energy), to the processes of cell division and growth regulation, and to the composition and replication of genetic material are just some of these changes. READ MORE
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3. Molecular mechanisms mediating development of pulmonary cachexia in COPD
Abstract : Cigarette smoking (CS) represents the main causative agent underlying development and progress of COPD. Recently, involvement of CS in the pathogenesis of COPDassociated muscle abnormalities is becoming increasingly evident. Nevertheless, involved triggers and underlying mechanisms remain largely unknown. READ MORE
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4. CYP26B1 as regulator of retinoic acid in vascular cells and atherosclerotic lesions
Abstract : Cardiovascular disease (CVD), currently the most common cause of morbidity and mortality worldwide, is caused mainly by atherosclerosis. Atherosclerosis is a chronic multifocal, immunoinflammatory, fibroproliferative disease of medium and large arteries. READ MORE
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5. DNA methylation in the placenta and in cancerwith special reference to folate transporting genes
Abstract : DNA methylation is an epigenetic mechanism that regulates the gene transcription. Folate is used in cellular synthesis of methyl groups, nucleic acids and amino acids. In complex diseases like cancer and neural tube defects (NTD), various genetic and epigenetic alterations can be found that disrupt the normal cell function. READ MORE