Search for dissertations about: "α-Amino aldehydes"
Found 5 swedish dissertations containing the words α-Amino aldehydes.
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1. Stereoselective Nucleophilic Additions to α-Amino Aldehydes: Application to Natural Product Synthesis
Abstract : This thesis deals with the development and application of new synthetic methodology for stereo- or regioselective construction of carbon-carbon bonds in organic synthesis. The first part of this thesis describes the development of a divergent protocol for stereoselective synthesis of chiral aminodiols by employing Mukaiyama aldol additions to syn- and anti-α-amino-β-silyloxy aldehydes. READ MORE
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2. Development of organocatalytic asymmetric transformations
Abstract : The ability of amino acids and amino acid derivatives to mediate various organocatalytic asymmetric transformations has been investigated and applied in the development of various reactions. This work describes the development of a direct catalytic asymmetric α-aminomethylation of ketones and aldehydes, a catalytic asymmetric aziridination, hydrophosphination and amination of α,β-unsaturated aldehydes. READ MORE
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3. Stereoselective Nucleophilic Additions to Aldehydes and Synthesis of α-Amino-β- Hydroxy-Esters
Abstract : This thesis deals with the development of new reaction methodology as well as stereochemical investigations. The first part concerns the investigation of 1,2- and merged 1,2- and 1,3- asymmetric induction in Mukaiyama aldol additions to α-heteroatom and α,β- heteroatom substituted aldehydes respectively. READ MORE
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4. Natural Product Synthesis and Development of Novel Reaction Methodology
Abstract : This thesis deals with the development of new reaction methodology for stereoselective synthesis, as well as total synthesis of natural products and investigations of the stereochemical outcome in the Mukaiyama aldol reaction. Chapter 2 describes efforts made towards the total synthesis of the oxindole natural products perophoramidine and the communesin. READ MORE
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5. Stereoselective Synthesis of Amino Alcohols : Applications to Natural Product Synthesis
Abstract : This thesis is divided into four separate parts with amino alcohols as the common feature. The first part of the thesis describes the development of an efficient three-component approach to the synthesis of α-hydroxy-β-amino esters. READ MORE
