Search for dissertations about: "β-catenin."
Showing result 11 - 15 of 73 swedish dissertations containing the word β-catenin..
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11. Molecular aspects of WNT/Frizzled signalling in brain angiogenesis
Abstract : The family of WNT lipoglycoproteins consists of 19 secreted proteins that are important for multiple cellular processes including cell proliferation, migration and fate. WNTs induce signalling cascades by binding the seven transmembrane receptors named Frizzleds (FZDs) classified as G protein-coupled receptors (GPCRs). READ MORE
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12. New Insights in Adrenal Tumourigenesis
Abstract : Unilateral cortisol producing adenoma (CPA) is the most common cause of ACTH-independent Cushing’s syndrome and is surgically curable. On the other hand, adrenocortical carcinomas (ACCs) are rare and aggressive tumours. READ MORE
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13. Mechanisms of Wnt signaling : from embryonic stem cells to dopaminergic neurons
Abstract : The ability of a cell to respond in a specific way to certain signals represents key biological phenomena governing development of multicellular organism. Cellular signaling regulates all aspects of cell biology such as proliferation, migration, differentiation, and death. READ MORE
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14. Mechanisms for TGF-β-Mediated Regulation of the Actin Filament System and Apoptosis
Abstract : Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participate in many different types of cellular processes, such as growth inhibition, cell migration, differentiation, cell adhesion, wound healing and immunosuppression. Alterations of TGF-β superfamily signalling results in several different disorders, including bone disease, vascular disease and cancer. READ MORE
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15. VEGF-B in islet of langerhans : role in vascular signaling and lipid handling
Abstract : The discovery of Vascular endothelial growth factor (VEGF)-B’s role in endothelial fatty acid uptake and tissue lipid accumulation opened a new arena for exploration of VEGF-B in lipid metabolism. Indeed, later studies demonstrated the beneficial/therapeutic effects of reducing VEGF-B signaling systemically. READ MORE