Search for dissertations about: "β-lactamase"
Showing result 11 - 15 of 29 swedish dissertations containing the word β-lactamase.
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11. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli
Abstract : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. READ MORE
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12. Interactions between innate immune effectors and multidrug resistant bacteria
Abstract : Antibiotic resistance is an increasingly difficult problem in the clinic, where conventional antibiotics are failing, and new alternative solutions are in high demand. Infections caused by Gram-negative bacteria with multi drug resistance (MDR) mechanisms are increasing globally, and treatment options are limited. READ MORE
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13. Dynamics and Mechanisms of Adaptive Evolution in Bacteria
Abstract : Determining the properties of mutations is fundamental to understanding the mechanisms of adaptive evolution. The major goal of this thesis is to investigate the mechanisms of bacterial adaptation to new environments using experimental evolution. READ MORE
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14. Immunocompromised Patients. Infections, Diagnostics and Nosocomial Transmission
Abstract : The aim of the work presented in this thesis was to improve the management of infections in immunocompromised patients by studying aspects of diagnostics, epidemiology and nosocomial transmission. Infection and rejection are common complications in lung-transplant patients, and early diagnosis and treatment are important for a positive outcome. READ MORE
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15. Invasive disease by Haemophilus influenzae in Sweden in the era of the H. influenzae type b vaccine
Abstract : What is the current status of Haemophilus influenzae as an agent of invasive infection in Sweden? H. influenzae type b (Hib) used to be a common cause of meningitis, epiglottitis and severe sepsis in young children. READ MORE