Search for dissertations about: "β2-agonist"

Found 4 swedish dissertations containing the word β2-agonist.

  2. 1. Effects of Asthma Combination Therapy on Extracellular Matrix Remodeling in Human Lung Fibroblasts

    Author : Lizbet Todorova; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Proteoglycans; Lung fibroblasts; Collagen; Airway remodeling; TGFβ; Glucocorticoids; Combination therapy.; β2-agonist; MMPs;

    Abstract : Fibroblasts, being one of the resident and structural cells of the lung, have the capacity to produce inflammatory mediators, cytokines and extracellular matrix (ECM) proteins perpetuating the inflammation in the airways of asthmatics. Airway remodeling is also a prominent feature of asthma that affects the lung function causing a thickening of the airways. READ MORE

  4. 2. Modulation of serous salivary gland function by the sympathetic nervous system : a biochemical and ultrastructural study with special reference to β-adrenoceptor subtypes

    Author : Roger Henriksson; Umeå universitet; []
    Keywords : Rat parotid gland; guinea-pig submandibular gland; ß-adrenoceptor subtypes; sympathetic denervation; sympathetic superstimulation; amylase secretion; cyclic AMP; ultrastructural stereology;

    Abstract : The aim of the present investigation was to study the influence of the sympathetic nervous system and of various adrenoceptor agents on enzyme secretion and morphology in rat parotid and guinea-pig submandibular glands. Biochemical methods were combined with electron microscopical techniques. READ MORE

  5. 3. Inflammation and cell migration in chronic obstructive pulmonary disease (COPD)

    Author : Kristin Blidberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic obstructive pulmonary disease (COPD), the fourth most common cause of death worldwide, is characterised by chronic airflow obstruction and chronic inflammation which affects large and, especially, small airways. There is an accumulation of inflammatory cells in the airways in COPD, in particular neutrophils, macrophages and CD8+ T-cells. READ MORE

  6. 4. Bronchoprovocation studies to define mechanisms in asthma and airway inflammation

    Author : Nikolaos Lazarinis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Bronchial provocations with a variety of stimuli have been widely used over the past 70 years in both asthma research as well as in daily clinical praxis in order to aid the physician to establish the asthma diagnosis. In research, the bronchoprovocation model represents an excellent tool to better understand asthma pathophysiology, and to assess the effects of different interventions and new investigational therapies. READ MORE