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Found 3 swedish dissertations matching the above criteria.

  1. 1. On the role of small regulatory molecules in the interplay between σ54- and σ70-dependent transcription

    Author : Linda Holmfeldt; Victoria Shingler; Thomas Nyström; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; σ54; σ70; ppGpp; DksA; transcription regulation; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Signal responsive transcriptional control in bacteria is mediated through both specific and global regulatory circuits to attune promoter output to prevailing conditions. Divergent transcription of a regulatory gene and a cognate promoter under its control provides an opportunity for interplay between transcription dependent on RNA polymerases utilizing various σ-factors, each of which programs the holoenzyme to recognize different classes of promoters. READ MORE

  2. 2. Deciphering control of Mechano-Transcription Activators of σ54-RNA polymerase

    Author : Henrik Seibt; Victoria Shingler; Uwe H. Sauer; Ray Dixon; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Transcriptional regulation; P. putida; V. cholerae; AAA ; bEBP; B-linker; DmpR; Phenol catabolism; VCA0117; Type VI secretion; molekylärbiologi; Molecular Biology;

    Abstract : To survive and proliferate, bacteria have to respond to a plethora of fluctuating signals within their habitats. Transcriptional control is one crucial entry point for such signal-responsive adaption responses. READ MORE

  3. 3. On the role of ppGpp and DksA mediated control of σ54-dependent transcription

    Author : Lisandro Bernardo; Victoria Shingler; Victor de Lorenzo; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ppGpp; DksA; σ54-transcription; global regulation; E. coli; P. putida; Molecular biology; Molekylärbiologi;

    Abstract : The σ54-dependent Po promoter drives transcription of an operon that encodes a suite of enzymes for (methyl)phenols catabolism. Transcription from Po is controlled by the sensor-activator DmpR that binds (methyl)phenol effectors to take up its active form. READ MORE