Search for dissertations about: "1,2 - amino alcohols"

Found 5 swedish dissertations containing the words 1,2 - amino alcohols.

  2. 1. Oxidation of 1,2-Diols Using Alcohol Dehydrogenases : From Kinetic Characterization to Directed Evolution

    Author : Cecilia Blikstad; Mikael Widersten; Stefan Lutz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; enzyme kinetics; alcohol dehydrogenase; directed evolution; enzyme engineering; diol; α-hydroxy aldehyde; Biokemi; Biochemistry;

    Abstract : The use of enzymes as catalysts for chemical transformations has emerged as a “greener” alternative to traditional organic synthesis. An issue to solve though, is that enzymes are designed by nature to catalyze reactions in a living cell and therefore, in many cases, do not meet the requirements of a suitable biocatalyst. READ MORE

  4. 2. Engineered Alcohol Dehydrogenases for Stereoselective Chemical Transformations

    Author : Thilak Reddy Enugala; Mikael Widersten; Manfred T. Reetz; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; alcohol dehydrogenase-A; biocatalysts; protein engineering; enzyme kinetics; sec-alcohols; ketones; stereoselectivity; regioselectivity; substrate selectivity and promiscuity.; Biokemi; Biochemistry;

    Abstract : Enzymes are biomolecules built from amino acids and catalyze the chemical transformations in a cell. Enzymes are by nature stereoselective, biodegradable, environmentally friendly, and can perform catalysis in aqueous solutions and at ambient temperatures. READ MORE

  5. 3. Synthesis and [3,3]-Sigmatropic Rearrangement of Vinylaziridines

    Author : Ulf Lindström; Torbjörn Frejd; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Abstract : A general synthetic route from vinylepoxides to vinylaziridines via 1,2-amino alcohols was developed. The 1,2-amino alcohols were obtained from a stereospecific and regioselective aminolysis of vinylepoxides. The synthetic scope of the aminolysis could be expanded by the use of a microwave-assisted protocol. READ MORE

  6. 4. Enzyme- and Transition Metal-Catalyzed Asymmetric Transformations : Application of Enzymatic (D)KR in Enantioselective Synthesis

    Author : Richard Lihammar; Jan-Erling Bäckvall; Wolfgang Kroutil; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dynamic Kinetic Resolution; Kinetic Resolution; Enzyme Catalysis; Asymmetric Synthesis; organisk kemi; Organic Chemistry;

    Abstract : Dynamic kinetic resolution (DKR) is a powerful method for obtaining compounds with high optical purity. The process relies on the combination of a kinetic resolution with an in situ racemization. READ MORE

  7. 5. Glycerol derivatives in the hydrogen autotransfer reaction - Development of C-C and C-N bond forming reactions

    Author : Anna Said Stålsmeden; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; amination; organic synthesis; sustainable precursors; alkylation; hydrogen autotransfer; glycerol;

    Abstract : Glycerol (1,2,3-propanetriol) is obtained as a byproduct in the biodiesel industry. In the quest for more sustainable starting materials for organic synthesis, glycerol with its three alcohol functionalities is a promising candidate. READ MORE