Search for dissertations about: "11β-Hydroxysteroid Dehydrogenase Type 1"
Found 3 swedish dissertations containing the words 11β-Hydroxysteroid Dehydrogenase Type 1.
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1. Adipose tissue as an active organ : blood flow regulation and tissue-specific glucocorticoid metabolism
Abstract : Background: Despite advances in the treatment of atherosclerosis, cardiovascular disease is the leading cause of death worldwide. With the population getting older and more obese, the burden of cardiovascular disease may further increase. READ MORE
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2. Estrogen and Glucocorticoid Metabolism
Abstract : Background: Cardiovascular disease (CVD) is the leading cause of death among women in Sweden. The risk of CVD increases rapidly after the menopause. A major contributing factor may be the redistribution of adipose tissue, from the peripheral to central depots, associated with menopause. READ MORE
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3. Disturbed Islet Function and Alterations in Islet Protein Expression
Abstract : Pancreatic β-cells sense the concentration of glucose in the systemic circulation through metabolism of the sugar molecule. Failure to correlate the blood sugar concentration to an appropriate metabolic signal disrupts the function of the β-cell as a controller of glucose homeostasis and may contribute to the development of type 2 diabetes mellitus. READ MORE