Search for dissertations about: "125I"

Showing result 1 - 5 of 49 swedish dissertations containing the word 125I.

  1. 1. Targeting Biological Systems by Organic Synthesis Methods - Cancer Cells and Proteins

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Cecilia Winander; Uppsala universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; carborane; doxorubicin; 125I; molecular recognition; four-helix bundle; polypeptide conjugate; affinity; chitinase; acetylcholine esterase; Organisk kemi;

    Abstract : This thesis describes the design and synthesis of molecules with potential roles in biomedicine, with an emphasis on molecular recognition in complex biological environments. The first chapter describes the synthesis and evaluation of compounds for use in nuclide therapy. READ MORE

  2. 2. EGFR and HER2 Targeting for Radionuclide-Based Imaging and Therapy Preclinical Studies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erika Nordberg; Uppsala universitet.; [2008]
    Keywords : Biomedicine; EGFR; HER2; affibody molecule; tumour targeting; 125I; 111In; Biomedicin;

    Abstract : The optimal way to detect and treat cancer is to target cancer cells exclusively without affecting the surrounding tissue. One promising approach is to use radiolabelled molecules to target receptors that are overexpressed in cancer cells. READ MORE

  3. 3. Two-Step Targeting for Effective Radionuclide Therapy Preclinical Evaluation of 125I-labelled Anthracycline Delivered by Tumour Targeting Liposomes

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Amelie Fondell; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radionuclide; Auger electrons; liposomes; targeting; tumour therapy; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Abstract : For the treatment of cancer, Auger-electron emitting radionuclides are strongly dependent on their close proximity to DNA to utilize the local therapeutic potential of the Auger electrons. This thesis investigates a two-step targeting approach that uses targeting liposomes for the delivery of an Auger-electron emitter, 125I, coupled to a DNA-binding compound, Comp1, to the tumour-cell DNA. READ MORE

  4. 4. Radionuclide targeting with particular empahsis on urinary bladder carcinoma

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anna Sjöström; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Abstract : The incidence of urinary bladder carcinoma is increasing and many patients die every year of this disease despite assumed radical therapy. Thus, there is a need for improved methods of diagnosis and therapy. READ MORE

  5. 5. Interaction of Triglyceride-rich Lipoproteins with Platelets and Vitamin K-dependent Coagulation Factors

    University dissertation from Department of Internal Medcine, University Hospital of Lund

    Author : Ning Xu; Lunds universitet.; Lund University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Triglycerides.; Prothrombin; Protein S; Protein C; Platelets; Phospholipids; Metabolism; Lipoproteins; Lipids; Endocytosis; Electron microscopy; Cytochemistry; Coronary heart disease; Blood coagulation factors; Arachidonic acid; Atherosclerosis; Clinical chemistry; Klinisk kemi; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : Popular Abstract in Swedish Hypertriglyceridemi (förhöjd plasma triglycerid(TG)nivå) är en riskfaktor för hjärt- kärlsjukdom. Det har föreslagits att relationen mellan fettintag och arterioskleros orsakas av vad som utspelar sig timmarna efter måltid. READ MORE