Search for dissertations about: "1866"

Showing result 1 - 5 of 19 swedish dissertations containing the word 1866.

  1. 1. Ex‘PLA’ining the progression of pathological proteins in Alzheimer’s and Parkinson’s diseases : see(d)ing is believing

    Author : Anish Behere; Joakim Bergström; Sara Ekmark-Lewén; Martin Ingelsson; Stina Syvänen; Hilal Lashuel; Uppsala universitet; []
    Keywords : Alpha synuclein; Tau; Proteoforms; Phosphorylation; Oligomers; Proximity Ligation Assay; sensitive detection of pathology; Alzheimer s disease; Parkinson s disease; pS129; pS202 pT205; pT231; PFFs;

    Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common forms of neurodegenerative disorders affecting approximately 50 million people worldwide. The underlying neuropathological processes leading to AD and PD share many similarities, i.e. aberrant protein aggregation of tau and alpha-synuclein (αSyn) in the brain. READ MORE

  2. 2. Non-Alcoholic Fatty Liver Disease : Insights into Alcohol Consumption, Genetics, and Proteomics

    Author : Julia Blomdahl; Stergios Kechagias; Mattias Ekstedt; Maja Thiele; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : NAFLD (Non-Alcoholic Fatty Liver Disease) affects approximately a quarter of the global population and is closely linked to type 2 diabetes mellitus and obesity. The disease spectrum ranges from steatosis and steatohepatitis to fibrosis, cirrhosis, and hepatocellular cancer. READ MORE

  3. 3. A geophysical investigation of carbonate build-ups in the Baltic Basin using reflection seismic and well data

    Author : Tegan Levendal; Christopher Juhlin; Lars Nielsen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Reflection seismic; Ordovician; Silurian; Carbonate mud mounds; Reefs; Gotland; Sweden; CAES; Seismic interpretation; OPAB dataset; 3D seismic; Geofysik med inriktning mot fasta jordens fysik; Geophysics with specialization in Solid Earth Physics;

    Abstract : During the Late Ordovician, the region around Gotland was part of a shallow epicratonic basin in the southern subtropics. Low latitudes, relatively warm sea temperatures and the presence of a shallow marine environment promoted algae to flourish and diverse carbonate build-ups such as carbonate mounds and reefs developed on the southern margin of Baltica. READ MORE

  4. 4. Towards Increased Use of Discrete-Event Simulation for Hospital Resource Planning

    Author : Krisjanis Steins; Jan Lundgren; Fredrik Persson; Sten Walther; Sally Brailsford; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Health care systems in many countries are experiencing a growing demand while their resources remain limited. The discrepancy between demand and capacity creates many problems – long waiting times for treatment, overcrowding in hospital wards, high workload, etc. READ MORE

  5. 5. Gait speed and physical exercise in people with dementia

    Author : Annika Toots; Erik Rosendahl; Håkan Littbrand; Yngve Gustafson; Stephen Lord; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exercise; dementia; residential facilities; postural balance; activities of daily living; cognitive function; mobility limitation; Alzheimer s disease; rehabilitation; frail elderly; gait speed; mortality; aged 80 and older;

    Abstract : The aim of the thesis was to investigate the importance of physical function for survival in very old people, and furthermore, whether physical exercise could influence physical function, cognitive function, and dependence in activities of daily living (ADLs) in older people with dementia living in nursing homes.The world’s population is ageing. READ MORE