Search for dissertations about: "2’-O-methylation"

Found 3 swedish dissertations containing the word 2’-O-methylation.

  2. 1. RNA-mediated gene expression regulation

    Author : Paula Petronela Groza; Francesca Aguilo; Yuri B. Schwartz; Silvia Remeseiro; Henrik Nielsen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA modifications; fibrillarin; 2 -O-methylation; translation; alternative splicing; METTL3; m6A; ZFP207; breast cancer; mouse ESCs; molekylärbiologi; Molecular Biology;

    Abstract : The regulation of gene expression is a key mechanism that underlies all biological processes, from embryonic development to the onset and progression of various diseases, including cancer. A growing body of evidence places RNA molecules at the center of critical regulatory steps in gene expression. READ MORE

  4. 2. RNA modifications and post-transcriptional control in cancer and stem cells

    Author : Giulia Beneventi; Avdelningen för molekylär hematologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA modifications; Pseudouridine; 2’-O-methylation; Splicing; Translation; non-coding RNAs; Cancer; Stem cells; Differentiation; Stress response;

    Abstract : Splicing and translation are two of the key steps of post-transcriptional regulation of gene expression. Their tight regulation is essential for development, whereas their deregulation is involved in cancer pathogenesis. Nevertheless, many of the molecular mechanisms controlling these processes are still unknown. READ MORE

  5. 3. Accuracy of protein synthesis and its tuning by mRNA modifications

    Author : Gabriele Indrisiunaite; Måns Ehrenberg; Suparna Sanyal; Jaanus Remme; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Protein synthesis; Translation; Accuracy; Release factor; Termination; mRNA modifications; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : The ribosome is a large macromolecular complex that synthesizes all proteins in the cell in all kingdoms of life. Proteins perform many vital functions, ranging from catalysis of biochemical reactions to muscle movement. It is essential for cells and organisms that proteins are synthesized rapidly and accurately. READ MORE