Search for dissertations about: "2 -terpyridine, toxicity"

Showing result 1 - 5 of 436 swedish dissertations containing the words 2 -terpyridine, toxicity.

  2. 1. Persistency, bioaccumulation and toxicity assessment of selected brominated flame retardants

    Author : Jenny Rattfelt Nyholm; Patrik L. Andersson; Peter Haglund; Mats Tysklind; Walter Vetter; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; persistence; bioaccumulation; toxicity; biodegradation; biotransformation; PBT; read across; soil; earthworm; zebrafish; copepod; BFRs; polybrominated diphenyl ethers; tetrabromobisphenol A; hexabromocyclododecane; hexabromobenzene; 2; 4; 6-tribromophenol; tetrabromobisphenol A; 2-hydroxyethyl ether; 1; 2-dibromo-4- 1; 2-dibromoethyl cyclohexane; Environmental chemistry; Miljökemi;

    Abstract : Brominated flame retardants (BFRs) are chemicals used in e.g. electronic equipment, textiles and plastics for the prevention of fire. Over recent decades, concern has been raised regarding some heavily used BFRs, since the levels in the environment have been increasing. READ MORE

  4. 2. Comparative avian developmental toxicity of PFAAs

    Author : Marcus Nordén; Magnus Engwall; Krister Halldin; Anders Bignert; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; chicken; herring gull; cormorant; PFAA; PFOS; PFOA; toxicity; levels; Biology; Biologi;

    Abstract : Perfluoroalkyl acids (PFAAs) are persistent organic pollutants that can commonly be found in environmental matrixes and wildlife from all over the globe. The PFAAs have been used in applications such as water and dirt repelling treatments for textiles, oil-resistant paper coatings and fire-fighting foams. READ MORE

  5. 3. Analysis of Perfluoroalkyl Acids in Swedish Biota : Temporal trends, tissue distribution and toxicity

    Author : Katrin Holmström; Urs Berger; Gregg Tomy; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; PFOS; PFAS; pollutant; Baltic guillemot; peregrine falcon; Monoporeia affinis; time trend; toxicity; Environmental chemistry; Miljökemi; Persistent organic compounds; Persistenta organiska föreningar; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : Perfluorinated alkyl acids (PFAS) are ubiquitous environmental contaminants. They are found in high concentrations in top predators worldwide, with perfluorooctane sulfonate (PFOS) as the predominant compound. READ MORE

  6. 4. Structures, toxicity and internalization of cell-penetrating peptides

    Author : Emelía Eiríksdóttir; Ülo Langel; Michael Gait; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CPP; cell-penetrating peptide; internalization; toxicity; structures; Neurochemistry; Neurokemi; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Cellular internalization is a highly regulated process controlled by proteins in the plasma membrane. Large and hydrophilic compounds, in particular, face difficulties conquering the plasma membrane barrier in order to gain access to intracellular environment. This puts serious constrains on the drug industry since many drugs are hydrophilic. READ MORE

  7. 5. Integrating Efficacy and Toxicity in Preclinical Anticancer Drug Development : Methods and Applications

    Author : Caroline Haglund; Elin Lindhagen; Rolf Larsson; Anna Åleskog; Sigurd Vitols; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticancer drugs; In vitro assays; Toxicity testing; Haematological toxicity; Primary tumour cells; Species difference; Clinical pharmacology; Klinisk farmakologi; Clinical Pharmacology; Klinisk farmakologi;

    Abstract : Preclinical testing is an important part of cancer drug development. The aim of this thesis was to establish and evaluate preclinical in vitro methods useful in the development of new anticancer drugs. In paper I, the development of non-clonogenic assays (FMCA-GM) using CD34+ stem cells for assessment of haematological toxicity was described. READ MORE