Search for dissertations about: "2- pyrimidine"

Showing result 21 - 23 of 23 swedish dissertations containing the words 2- pyrimidine.

  1. 21. Novel functions of cardiovascular P2 receptors

    University dissertation from Anna-Karin Wihlborg, Department of Cardiology, Lund University

    Author : Anna-Karin Wihlborg; Lund University.; Lunds universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; mRNA; EDHF; UTP; UDP; ADP; ATP; P2 receptor; contraction; dilatation; endothelial cells; Heart; VSMC;

    Abstract : The aim of the thesis was to examine the expression and function of the extracellular nucleotide P2 receptors in the cardiovascular system. In the cardiovascular system nucleotides are released during shear stress, hypoxia, ischemia, from endothelial cells, smooth muscle cells, aggregating platelets, inflammatory cells and erythrocytes. READ MORE

  2. 22. NMR studies of DNA structure and counterion behaviour

    University dissertation from Stockholm : Stockholm University

    Author : Lorens van Dam; Stockholms universitet.; [2000]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical Chemistry; fysikalisk kemi;

    Abstract : DNA is a polymer of nucleotides, each nucleotide consisting of a negatively charged phosphate group, a ribose sugar unit, and a purine or pyrimidine base. The secondary structure of DNA is commonly a double-helix with Watson-Crick paired bases. Several secondary structures, all with these features, are observed for DNA. READ MORE

  3. 23. Small molecules that affect the p53 pathway and their potential use in the treatment of cancer

    University dissertation from Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology

    Author : Marijke Cornelia Christine Sachweh; Karolinska Institutet.; Karolinska Institutet.; [2014]

    Abstract : The tumor suppressor p53 was identified 35 years ago and has since then been studied extensively, but despite all efforts, no drug or therapy directly involving it has been clinically approved - yet! A lot of potential new drugs are on their way that can reactivate p53 function by various mechanisms. Even a whole new approach called cyclotherapy has been established, during which p53 is activated in normal cells to protect patients from the adverse effects of chemotherapy while tumor cells are still being killed efficiently. READ MORE