Search for dissertations about: "2-D electrophoresis"

Showing result 1 - 5 of 13 swedish dissertations containing the words 2-D electrophoresis.

  2. 1. Unwarping and Analysing Electrophoresis Gels

    Author : John Gustafsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURAL SCIENCES; Classification; Curved field lines; Gel matching; Image alignment; Image warping; Proteomics; Pulse-field gel electrophoresis; Two-dimensional electrophoresis; Variation; Yeast; Gel matching;

    Abstract : Gel electrophoresis is a technology in molecular biology that is used to separate and quantify biomolecules, for example DNA and proteins. Ideally the position in a gel image corresponds to one or several properties of the molecules, such as size and net charge, but in practise the separation pattern is often warped, that is, geometrically distorted. READ MORE

  4. 2. The Bronchoalveolar Lavage Proteome- Phenotypic associations to smoking and divergence towards development of COPD

    Author : Amelie Plymoth; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; mass spectrometry; proteomics; 2-D gel; COPD; bronchoalveolar lavage;

    Abstract : Proteomic analysis of bronchoalveolar lavage (BAL) fluid from smokers at risk of developing chronic obstructive pulmonary disease (COPD) and never smokers is described. COPD is currently the world's fourth leading cause of death and its prevalence is increasing. READ MORE

  5. 3. Studies of immune responses to cell surface proteins of Helicobacter pylori and Borrelia burgdorferi by enzyme immunoassay and immunoblotting

    Author : Ingrid Nilsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; B. burgdorferi; H.pylori; cell surface proteins; gel-electrophoresis; enzyme immunoassay; Western immunoblotting; bacteriology; Microbiology; bakteriologi; virologi; mykologi;

    Abstract : Helicobacter pylori and Borrelia burgdorferi s.l. can cause chronic infections by evading the immune system. These two human pathogens express a number of immunogenic cell surface proteins. READ MORE

  6. 4. Bronchoalveolar lavage and serum protein patterns in healthy individuals and sarcoidosis patients : a proteomics approach

    Author : Fariba Sabounchi Schütt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sarcoidosis; BALF; serum; proteomics; 2-D electrophoresis; protein-spot pattern; protein identification;

    Abstract : The etiology of sarcoidosis remains unknown. Although biochemical changes are frequently observed in sarcoidosis, the problem of finding distinct biomarkers remains. Only a few markers are defined in this disease. READ MORE

  7. 5. Helicobacter pylori bacterial diversity and human disease : microbiological and epidemiological studies with special reference to gastric cancer

    Author : Helena Enroth; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Helicobacter Pylori; microbiology; epidemiology; diversity; gastric adenocarcinoma; risk factors; coccoid; genomic fingerprinting; strain variation; multiple strain infection; PCR; 2-D PAGE; immunoblotting; CagA; VacA;

    Abstract : The aims of this thesis were to explore if the coccoid form of H. pylori is a degenerative, dead form of the bacteria. We also wanted to study if multiple strain infections of H. pylori existed in Swedish subjects, if the strain variations were connected to certain disease groups, and if specific protein markers could be found in H. READ MORE