Search for dissertations about: "2-nitrofluorene"

Found 3 swedish dissertations containing the word 2-nitrofluorene.

  1. 1. Studies on DNA adducts and carcinogenesis with 2-nitrofluorene as a model substance

    Author : Xian-Shu Cui; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; 2-nitrofluorene; carcinogens; DNA adducts; preneoplastic lesion; tumor;

    Abstract : Studies on DNA Adducts and Carcinogenesis with 2-Nitrofluorene as a Model Substance Xian-Shu Cui Center for Nutrition and Toxicology Department of Biosciences at Novum, Karolinska institute Novum, S-141 57 Huddinge, Sweden A number of carcinogens or their electrophilic intermediates are able to bind covalently to DNA, forming DNA adducts. DNA adducts may cause gene mutations if they are misrepaired or remain unrepaired before DNA replication occurs. READ MORE

  2. 2. Aspects of the regulation of human sperm motility

    Author : Pär K.G. Leijonhufvud; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : In this thesis I address some of the possible causes for oligozoospermia and low sperm motility, two factors that, singly or in combination, are often seen in cases of male subfertility. In the first study we evaluated the effect on human spermatozoa of the toxicity of compounds present in diesel exhaust. READ MORE

  3. 3. High-performance liquid chromatography for analysis of 32P-Postlabeled DNA adducts

    Author : Magnus Zeisig; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; DNA adducts; 32P-postlabeling; HPLC; method development;

    Abstract : High-Performance Liquid Chromatography for Analysis of 32P-Postlabeled DNA Adducts Magnus Zeisig Center for Nutrition and Toxicology, Department of Bioscience at Novum, Karolinska Institutet, Novum, S-141 57 Huddinge, SwedenThe formation of DNA adducts, i.e. READ MORE