Search for dissertations about: "2010 medical biochemistry thesis"
Showing result 1 - 5 of 27 swedish dissertations containing the words 2010 medical biochemistry thesis.
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1. The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells : Investigations in vitro and in Reactive Tissues in vivo
Abstract : Pericytes are cells of mesenchymal origin located on the abluminal side, juxtapositioned to the endothelial cells in capillaries, venules and small arterioles. They are important for maintaining vessel integrity in resting tissues as well as the formation and stabilization of new vessels. READ MORE
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2. Studies of in vivo prostate amyloidosis and autoimmune responses towards amyloid structures in neurodegeneration
Abstract : By using multidisciplinary analysis of CA inclusions in prostate glands of patients diagnosed with prostate cancer, we have revealed that their major components are the amyloid forms of S100A8 and S100A9 proteins associated with numerous inflammatory conditions and types of cancer. We have demonstrated that material closely resembling CA can be produced from S100A8/A9 in vitro and shows the characters of amyloids. READ MORE
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3. Lipase-Catalyzed Syntheses of Telechelic Polyesters
Abstract : Telechelic polyesters have successfully been synthesized with lipase-catalyzed polymerization. The produced telechelics had a high degree of difunctionalization, high purity (requiring little or no workup) and controlled degree of polymerization. The syntheses were performed in one-pot one-step reaction systems. READ MORE
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4. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors
Abstract : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). READ MORE
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5. Lipase Specificity and Selectivity : Engineering, Kinetics and Applied Catalysis
Abstract : The specificity and selectivity of the enzyme Candida antarctica lipase B (CALB) were studiedfor several substrates and applications.With help of molecular modeling, the active site of CALB was redesigned for the ring openingpolymerization of D,D‐lactide. READ MORE