Search for dissertations about: "2013 and genetic"

Showing result 1 - 5 of 183 swedish dissertations containing the words 2013 and genetic.

  2. 1. Osteogenesis Imperfecta : Genetic and Therapeutic Studies

    Author : Katarina Lindahl; Östen Ljunggren; Andreas Kindmark; Carl-Johan Rubin; David Sillence; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; OI; BMD; Genotype; Phenotype; Pharmaco-genetics; Bisphosphonate; Therapy; Gene-therapy; Mutation; Collagen; Collagen type I; Allele-specific silencing; siRNA; RNAi; COL1A1; COL1A2; Stroke; C-propeptide; Mineralization; Heterozygous disadvantage; Genetics; Genetik; Medicin; Medicine; Medical Genetics; Medicinsk genetik;

    Abstract : Osteogenesis imperfecta (OI) is a heterogeneous disease of connective tissue, the cardinal symptom being fractures and severity ranging from mild to lethal. Dominant mutations in collagen I, encoded by COL1A1 and COL1A2, cause >90% of cases. READ MORE

  4. 2. Genomic and genetic alterations in endometrial adenocarcinoma

    Author : Eva Falck; Karin Klinga-Levan; Afrouz Behboudi; Pierre Åhman; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; Genetic background; BDII rat model; SKY; Chromosomal abreations; Gene expression; Medicine; Medicin; Natural sciences;

    Abstract : The most frequently diagnosed cancer of the female genital tract is cancer of the endometrium (endometrial cancer), ranking fourth among the invasive tumors that affect women in Europe and North America. As most other cancer types, endometrial cancer is a complex genetic disease influenced by both genetic and environmental factors. READ MORE

  5. 3. Logistics of Earthmoving Operations : Simulation and Optimization

    Author : Jiali Fu; Haris Koutsopoulos; Andreas Tapani; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Earthworks are a fundamental part of heavy construction engineering and involve the moving and processing of the soil surface of earth. Normally, earthmoving operations are carried out during the early stages of heavy construction projects. READ MORE

  6. 4. NFAT signaling in chronic and acute inflammation - A novel target for the treatment of diabetic vascular complications and acute pancreatitis?

    Author : Anna Zetterqvist; Diabetiska komplikationer; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NFAT; vascular; diabetes; inflammation; atherosclerosis; diabetic retinopathy; acute pancreatitis; osteopontin; VCAM-1; A-285222;

    Abstract : Diabetic patients suffer from macro- and microvascular complications causing increased morbidity and mortality. How hyperglycemia provokes vascular damage remains unclear, but glucose is believed to fuel a harmful low-grade chronic inflammation of the vessel wall. READ MORE

  7. 5. Turner karyotype and childbirth

    Author : Anna Hagman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Turner syndrome; obstetric and neonatal outcome; Turner karyotype; pregnancy; maternal characteristics; neonatal chracterisitics;

    Abstract : Turner karyotype and childbirth Anna Hagman, Department of Obstetrics and Gynaecology, Institute of Clinical Sciences, the Sahlgrenska Academy, University of Gothenburg, Sweden, 2013. anna.c.hagman@vgregion. READ MORE