Search for dissertations about: "3’UTR"

Showing result 1 - 5 of 22 swedish dissertations containing the word 3’UTR.

  2. 1. Real-time PCR and its application for protein quantification

    Author : Kristina Lind; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ELISA; real-time immuno-PCR; real-time PCR; melt curve analysis; PSA; 3’UTR; TAP-tag; BOXTO; immuno-qPCR;

    Abstract : The ability to quantify specific DNA sequences with real-time PCR has increased the possibilities for sensitive DNA analysis enormously. This sensitive technique can in optimal conditions detect one DNA copy and has a large quantification range. READ MORE

  4. 2. Regulation of RNA Processing in Human Papillomavirus Type 16

    Author : Margaret Rush; Stefan Schwartz; Jörgen Kjems; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; RNA processing; human papillomavirus; HPV-16; alternative splicing; polyadenylation; exonic splicing enhancer; 3 UTR; upstream polyadenylation element; SR proteins; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Human papillomavirus type 16 (HPV-16) is the major cause of cervical cancer. HPV-16 gene expression is tightly linked to the differentiation programme of the infected epithelium. Expression of the late genes, L1 and L2, encoding the capsid proteins, is delayed until the more terminally differentiated cells. READ MORE

  5. 3. European Black Grouse : MHC Genetic Diversity and Population Structure

    Author : Tanja Strand; Jacob Höglund; Helena Westerdahl; David S. Richardson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Major Histocompatibility Complex; BLB; balancing selection; concerted evolution; bottleneck; fragmentation; 3 UTR; Biologi med inriktning mot populationsbiologi; Biology with specialization in Population Biology;

    Abstract : Black grouse Tetrao tetrix is a bird species composed of large, continuous as well as severely reduced and fragmented populations, making it an optimal species to investigate how genetic diversity is affected by habitat fragmentation. I have focused on genetic diversity in the Major Histocompatibility Complex (MHC) to measure the ability of the black grouse to respond to environmental changes. READ MORE

  6. 4. Role of the 3'UTR in translation and stability of HCV and HPV mRNAs

    Author : Lisa Wiklund; Laszlo Szekely; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hepatitis C virus; Human Papillomavirus; 3’ untranslated region; AU-rich sequence; mRNA stability; translation; Biokemi; Biochemistry; Biokemi; Medical Virology; medicinsk virologi;

    Abstract : Virus mRNAs can be divided into functional regions. The focus of this thesis will be to investigate the function of one of these regions, the 3’ untranslated region (UTR). The 3’UTR of HCV contains a U-rich element and the late 3’UTR of HPV-1 contains an AU-rich element. READ MORE

  7. 5. Post-Transcriptional Regulation of the Murine Inducible Nitric Oxide Synthase Gene

    Author : Malin Söderberg; Matti A. Lang; Françoise Raffalli-Mathieu; Eeva Moilanen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; iNOS; inducible nitric oxide synthase; gene regulation; post-transcriptional; mRNA stability; RNA-protein interactions; dexamethasone; murine; heterogeneous nuclear ribonucleoprotein; hnRNPI; hnRNPL; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi;

    Abstract : Large amounts of nitric oxide (NO) are produced by the inducible nitric oxide synthase (iNOS) upon inflammatory stimuli. NO is a multifaceted molecule, which may have beneficial effects as an antimicrobial agent in the immune defense, or cytotoxic effects in chronic inflammations, manifested as e.g. arthritis and asthma. READ MORE