Search for dissertations about: "32P-postlabelling"

Showing result 6 - 7 of 7 swedish dissertations containing the word 32P-postlabelling.

  2. 6. ³²P-postlabelling analysis of DNA adducts in fish as a biomarker of genotoxic exposure

    Author : Gunilla Ericson; Tracy K Collier; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; zoologisk ekologi; Animal Ecology;

    Abstract : The 32P-postlabelling assay was used for analysis of hydrophobic DNA adducts in fish as a biomarker of genotoxic exposure. DNA adducts were analysed in perch (Perca fluviatilis) and northern pike (Esox lucius), two relatively stationary fish species which are common in Swedish freshwater systems and along the Baltic coast. READ MORE

  4. 7. Method development for analysis of 8-oxodG as a biomarker for oxidative stress

    Author : Tim Hofer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Oxidative damage to DNA gives oxidation of DNA bases and strand breaks that can cause mutations leading to cancer. Various forms of agents are capable of oxidising DNA in vivo including peroxides, singlet oxygen and UV- or gamma-irradiation. Oxidation of DNA bases occurs mainly at dG, giving stable DNA adducts such as 8-oxodG and FapydG. READ MORE