Search for dissertations about: "3D cell-culture"

Showing result 16 - 20 of 37 swedish dissertations containing the words 3D cell-culture.

  2. 16. Endometrial receptivity and human embryo implantation : in vivo and in vitro studies

    Author : Sujata Lalit Kumar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 3D-endometrial cell construct;

    Abstract : Background: Infertility, one of the common gynaecological disorders, affects 10-15% women in their reproductive years. Despite the advances in assisted reproduction techniques and the best efforts of infertility specialists, implantation rates do not exceed more than 28-30%. READ MORE

  4. 17. Fabrication advances of microvasculature models on-chip

    Author : Federico Cantoni; Maria Tenje; Niels Larsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 2-photon polymerization 3D printing; multi-hydrogel structure; vascula-ture model; microphysiological systems; organ-on-chip;

    Abstract : Despite the technological advances of the last decades, drug development remains a lengthy and costly process with uncertainties still associated with the poor predictive power of the in vitro and animal models. To address this limitation, microphysiological systems have been introduced in an attempt to increase the biological relevance of in vitro devices. READ MORE

  5. 18. Asymmetric Cellular Microenvironments

    Author : Susanna Rydholm; Hjalmar Brismar; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik;

    Abstract : This thesis presents methods to combine 3D cell culture, microfluidics and gradients on a controlled cellular scale. 3D cultures in biological extracellular matrix gels or synthetic gels bridge the gap between organ-tissue cultures and traditional 2D cultures. READ MORE

  6. 19. Hyaluronan Based Biomaterials with Imaging Capacity for Tissue Engineering

    Author : Yu Zhang; Dmitri Ossipov; Carsten Werner; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronan; hydrogel; scaffold; tissue engineering; imaging; interpenetrating network; MRI; fluorescence imaging; scaffold degradation;

    Abstract : This thesis presents the preparation of hyaluronan-based biomaterials with imaging capability and their application as scaffolds in tissue engineering. First, we have synthesized HA derivatives functionalized with different chemoselective groups. READ MORE

  7. 20. Tunable and modular assembly of polypeptides and polypeptide-hybrid biomaterials

    Author : Christopher Aronsson; Daniel Aili; Karin Enander; Staffan Dånmark; Dennis Löwik; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Biomaterials are materials that are specifically designed to be in contact with biological systems and have for a long time been used in medicine. Examples of biomaterials range from sophisticated prostheses used for replacing outworn body parts to ordinary contact lenses. Currently it is possible to create biomaterials that can e.g. READ MORE