Search for dissertations about: "3D cell-culture"
Showing result 21 - 25 of 37 swedish dissertations containing the words 3D cell-culture.
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21. Human iPSC-derived neuronal networks. Development and application for compound evaluation
Abstract : Research on human brain development and function in health and disease has been hampered by limited access to primary human tissue and limited translatability of animal studies. This knowledge gap is encouraging the use of human induced pluripotent stem cell (hiPSC)-derived neural in vitro models. READ MORE
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22. MEMS Interfaces for Bioanalysis Systems
Abstract : This thesis deals with various aspects of using open microfluidic interfaces. Three specific areas of application are studied. The first is air-to-liquid interfacing in biosensors with possibilities for component integration. A micromachined interface for airborne sample-to-liquid and droplet-to-liquid adsorption is discussed. READ MORE
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23. Generation and investigation of neural microenvironment in health and disease
Abstract : Cells in our body are under the constant influence of intrinsic and extrinsic factors that modulate their behavior. Early on, starting during the development of the organism, growth factors, nutrients, oxygen, the extracellular matrix and contact with other cells affect essential processes such as proliferation, migration, differentiation and apoptosis. READ MORE
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24. The human pancreatic polypeptide receptor Y4 : Genetic and functional variation
Abstract : Humans are evolutionarily adapted to an environment where food is scarce, but today many live in a world of food abundance. Paired with low physical activity, this may lead to weight gain and obesity. Efficient anti-obesity treatments require understanding of the mechanisms that control hunger, satiety, energy metabolism and body weight. READ MORE
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25. Organic Electronics and Microphysiological Systems to Interface, Monitor, and Model Biology
Abstract : Biological processes in the human body are regulated through complex and precise arrangements of cell structures and their interactions. In vivo models serve as the most accurate choice for biological studies to understand these processes. However, they are costly, time-consuming, and raise ethical issues. READ MORE