Search for dissertations about: "5 aminolevulinic acid"

Showing result 1 - 5 of 13 swedish dissertations containing the words 5 aminolevulinic acid.

2. 1. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

   Author : Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

   Abstract : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. READ MORE

4. 2. A theoretical study of 5-Aminolevulinic acid and its esters : properties and lipid permeability

   Author : Edvin Erdtman; Leif Eriksson; Fahmi Himo; Örebro universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biophysical chemistry; Biofysikalisk kemi; fysikalisk kemi; Physical Chemistry;

   Abstract : 5-aminolevulinic acid (5ALA) is a widely used prodrug in Photodynamic therapy (PDT). The target molecule in 5ALA-PDT is Protoporphyrin IX (PpIX), which is synthesized endogenously via the heme pathway in the cell. READ MORE

5. 3. Fluorescence Spectroscopy for Quantitative Demarcation of Glioblastoma Using 5-Aminolevulinic Acid

   Author : Neda Haj-Hosseini; Karin Wårdell; Göran Salerud; Peter E Andersen; Linköpings universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Abstract : Total resection of glioblastoma, the highly malignant brain tumor, is difficult to accomplish due to its diffuse growth and similarity to the surrounding brain tissue. A total resection is proven to increase patient survival. READ MORE

6. 4. ALA and m-ALA in bicontinuous lipid formulations: -Characterization and Transdermal Delivery

   Author : Johanna Bender; Chalmers tekniska högskola; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; passive diffusion; SAXS; monoolein; methyl 5-aminolevulinate hydrochloride; NMRD; sponge phase; 5-aminolevulinic acid hydrochloride; iontophoresis;

   Abstract : δ-Aminolevulinic acid (ALA) and its methyl ester (m-ALA) are both used in photodynamic therapy (PDT) of certain non melanoma skin cancers as the basal cell carcinoma (BCC). In PDT the cancer cells are destroyed by a photochemical reaction that occurs when a photosensitive molecule is irradiated with light of a certain wavelength. READ MORE

7. 5. Photodynamic therapy in the head and neck

   Author : Mathias von Beckerath; Claes Möller; Göran Laurell; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Photo Dynamic Therapy; Cancer; Skin; Larynx; 5-ALA; UVradiation; sarcoma; squamous cell carcinoma; porfimer sodium; temoporfin; voice; Kirurgi; Surgery;

   Abstract : Photodynamic therapy, PDT, is a method to diagnose and treat cancer. In PDT a sensitizer is administered to the patient and this sensitizer is accumulated in tumors. If the sensitizer-containing tumor is subjected to a laser of a specific wavelength the tumor is fluorescing allowing diagnostics. READ MORE