Search for dissertations about: "5-ALA"
Found 4 swedish dissertations containing the word 5-ALA.
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1. Photodynamic therapy in the head and neck
Abstract : Photodynamic therapy, PDT, is a method to diagnose and treat cancer. In PDT a sensitizer is administered to the patient and this sensitizer is accumulated in tumors. If the sensitizer-containing tumor is subjected to a laser of a specific wavelength the tumor is fluorescing allowing diagnostics. READ MORE
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2. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions
Abstract : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. READ MORE
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3. Fluorescence Guided Resection of Brain Tumors : Evaluation of a Hand-held Spectroscopic Probe
Abstract : Malignant gliomas grow infiltrative in the brain and can therefore not be completely removed by neurosurgical means. However, for an optimized oncological treatment it has proven useful to resect as much as possible of tumor. The identification of the tumor in the marginal zone is difficult but crucial. READ MORE
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4. Fluorescence Spectroscopy for Quantitative Demarcation of Glioblastoma Using 5-Aminolevulinic Acid
Abstract : Total resection of glioblastoma, the highly malignant brain tumor, is difficult to accomplish due to its diffuse growth and similarity to the surrounding brain tissue. A total resection is proven to increase patient survival. READ MORE