Search for dissertations about: "5-HT1A receptor"
Showing result 11 - 15 of 50 swedish dissertations containing the words 5-HT1A receptor.
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11. Clozapine as a dopamine D₁ receptor agonist
Abstract : Objectives'. The present study had two major objectives; [1] to examine the specific role of dopamine D, and DM receptors in body temperature regulation in rats, and [2] to examine in vivo dopamine D, and Dm receptor agonist/antagonist properties of clozapine by use of core temperature measurements.Methods'. READ MORE
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12. Development of radioligands for the serotonergic neurotransmission system for use in positron emission tomography
Abstract : The serotonergic system is implicated in several neuropsychiatric disorders, such as depression, anxiety and schizophrenia. Several hypotheses on the pathophysiology of these disorders are based on the pharmacology of serotonergic drugs. Selective serotonin reuptake inhibitors (SSRIs) are widely used for the treatment of depression and anxiety. READ MORE
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13. Development of positron emission tomography radioligands for the dopaminergic and serotonergic neurotransmission systems
Abstract : The dopaminergic and serotonergic neurotransmission systems are of central interest in relation to several neuropsychiatric disorders. The main objectives were to develop new suitable radioligands for positron emission tomography (PET) examinations of the dopamine transporter (DAT) as well as the serotonin 5-HT1A and 5-HT2A-receptors. READ MORE
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14. Regulation of insulin signaling and its developmental and functional roles on peptidergic neurons in the Drosophila central nervous system
Abstract : In Drosophila, eight insulin-like peptides (DILP1-8) are produced and secreted in different locations. They regulate many aspects of development and physiology, such as organism growth, metabolic homeostasis, reproduction, stress resistance and life span. READ MORE
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15. PET evaluation of central serotonergic neurotransmission in women
Abstract : The serotonin (5-HT) system is of central interest in the patophysiology and treatment of several psychiatric disorders including depression, anxiety and suicide. In women, functioning of the 5-HT system is of particular importance since they have been found to suffer more often from 5-HT-associated disorders compared to men. READ MORE