Search for dissertations about: "5-HTTLPR"

Showing result 1 - 5 of 10 swedish dissertations containing the word 5-HTTLPR.

  1. 1. A Biopsychosocial and Long Term Perspective on Child Behavioral Problems : Impact of Risk and Resilience

    Author : Sara Agnafors; Carl Göran Svedin; Gunilla Sydsjö; Anders Broberg; Linköpings universitet; []

    Abstract : Mental health has become a prominent issue in society. Yet, much remains unknown about the etiology of psychiatric disorders. The aim of the present thesis was to investigate the association between biological, psychological and social factors of risk and resilience and behavioral problems in a birth cohort of Swedish children. READ MORE

  2. 2. On the influence of serotonin- and sex steroid-related genetic variation on mood, anxiety, personality, autism and transsexualism

    Author : Susanne Henningsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : serotonin; 5-HTTLPR; TPH2; 5-HT3; sex steroids; androgen receptor; estrogen receptor; genetics; gene-gene interaction; social phobia; anxiety; premenstrual dysphoric disorder; depression; personality; autism; transsexualism; amygdala; emotional perception; life events;

    Abstract : Background: The neurotransmitter serotonin has been related to mood and anxiety, and variation in genes that encode important members of the serotonergic system may hence affect mood- and anxiety-related traits. Sex steroids influence brain development, and variation in genes encoding androgen and estrogen receptors, or enzymes needed for sex steroid synthesis, may be of importance for both personality traits and risk for psychiatric disorders. READ MORE

  3. 3. Genetic gating of human fear, fear learning and extinction : psychophysiological, brain imaging (fMRI) and clinical studies

    Author : Tina B Lonsdorf; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Individuals differ in their reaction to the same environmental stressor. After being opposed to the same trauma, some individuals will develop affective pathologies, while others will not. This is assumed to result, at least partly, from a differential genetic vulnerability. READ MORE

  4. 4. Molecular imaging of the serotonin system in human behaviour

    Author : Jacqueline Borg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : positron emission tomography; serotonin; 5-HT1A receptor; 5-HTT; 5HTTÖPR; WAY100635; MADAM; cognitive functions; personality;

    Abstract : The serotonin (5-HT) neurotransmission system has a role in essential physiological and psychological functions such as sleep, eating behaviour, sexuality, perception, emotion and cognition. Individual measures of serotonin biomarkers in the living human brain can be obtained using positron emission tomography (PET) imaging, direct measures of. READ MORE

  5. 5. Influence of serotonin-related genes on behavior and body weight

    Author : Jessica Bah Rösman; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Serotonin; Genes; anorexia nervosa; premenstrual dysforia; body weight; suicide; polymorphism; HTR2C; SLC6A4; GATA2; HTR3B;

    Abstract : Rationale: The neurotransmitter serotonin has been implicated in the regulation of normal behaviors, including food intake, and attributed importance for a variety of common psychiatric conditions, including major depression, suicidal behavior, eating disorders and premenstrual dysphoria. The purpose of these studies was to explore the possible influence of genetic variation in serotonin-related genes on a) body weight, b) binding capacity of the serotonin transporter in the brain of suicide attempters and c) a disorder for which numerous findings suggest serotonin to play a key role, i. READ MORE