Search for dissertations about: "5-HTTLPR"

Showing result 6 - 10 of 10 swedish dissertations containing the word 5-HTTLPR.

  2. 6. Genetic and experimental studies of seasonal affective disorder and related phenotypes

    Author : Carolina Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Seasonal affective disorder (SAD) is a subtype of recurrent depressive or bipolar disorder, in which episodes reoccur and remit during a particular season each year. A genetic component in vulnerability to winter SAD has been suggested, and the goal of this thesis was to increase the understanding of SAD and seasonal variations in mood, by obtaining self-report assessments of related traits, examining genetic variations in genes hypothesised to influence the phenotypes in question, and to investigate effects of different photoperiods and stress in an animal model. READ MORE

  4. 7. Emotional orientation, brain function and genetics in adults and children : implications for development, and psychopathology

    Author : Kara M Lindstrom; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The ability to attend or avoid emotional stimuli is important to our survival. Attending to potential threats can help us avoid danger; while attending to positive stimuli is important for our social function. For example, when we see a man with a knife it is important to run away, or avoid the threat so we are not harmed. READ MORE

  5. 8. Importance of serotonin-related candidate genes for human behaviour

    Author : Jonas Melke; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serotonin; genetics; polymorphism; association study; personality; panic disorder; premenstrual dysphoria; serotonin receptor; serotonin transporter;

    Abstract : Family and twin studies have been consistent in demonstrating that genetic factors are involved in the etiology of most major psychiatric disorders, as well as in various normal personality traits. Mostly due to the efficacy of serotonin-acting drugs, such as selective serotonin reuptake inhibitors (SSRI) and tricyclic antidepressants (TCA), the neurotransmitter serotonin has been implicated in a variety of common psychiatric disorders, including depression, a spectrum of anxiety disorders, and premenstrual dysphoria; moreover, some studies have suggested that also personality is influenced by serotonin. READ MORE

  6. 9. Neuropsychological functions in women with borderline personality disorder and a history of suicide attempts

    Author : Liselotte Maurex; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Borderline personality disorder (BPD) is a complex psychiatric disorder that leads to intense suffering for afflicted individuals, and extensive use of health care resources. Self-injurious and suicidal behaviors are common among individuals diagnosed with BPD, and as many as 10% of these will eventually die from suicide. READ MORE

  7. 10. Gene-Environment Interaction in Adolescent Deviant Behaviour

    Author : Kent W. Nilsson; Leif Lindström; Lars Oreland; Jerzy Leppert; John Öhrvik; Rickard L. Sjöberg; Marie Åsberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurobiology; Adolescent; Alcohol; Criminology; Genes; Environment; Monoamine Oxidase; Serotonin; Social Support; Neurobiologi; Neurobiology; Neurobiologi;

    Abstract : The overall aim of this thesis was to explore gene-environmental (G*E) interactions in relation to deviant behaviour among 200 Swedish adolescents, with a focus on criminality, alcohol consumption and depressive symptoms. Those behaviours have been extensively investigated in relation to both psychosocial and biological risk factors. READ MORE