Search for dissertations about: "5-hydroxy tryptophan"

Found 3 swedish dissertations containing the words 5-hydroxy tryptophan.

  1. 1. Engraftment of Pancreatic Islets in Alternative Transplantation Sites and the Feasibility of in vivo Monitoring of Native and Transplanted Beta-Cell Mass

    Author : Daniel Espes; Per-Ola Carlsson; Joey Lau; Mia Phillipson; Eelco de Koning; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Islet transplantation; Alternative implantation sites; Exendin-4; Positron Emission Tomography; 5-hydroxy tryptophan; Beta-cell mass; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Islet transplantation is a possible curative treatment for type 1 diabetes (T1D). Currently the liver dominates as implantation site, despite the many challenges encountered at this site.Acute hypoxia in islets transplanted to muscle and omentum, two possible alternative sites, was prevailing. READ MORE

  2. 2. Positron Emission Tomography in the Management of Neuroendocrine Tumors

    Author : Håkan Örlefors; Barbro Eriksson; Mats Bergstrom; Anders Sundin; Karel Pacak; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Neuroendocrine tumor NET ; carcinoid; endocrine pancreatic tumor EPT ; Positron Emission Tomography PET ; serotonin-precursor; 5-hydroxytrytophan 5-HTP ; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicin; Medicine;

    Abstract : Neuroendocrine tumors (NET´s) are often characterized by overproduction of peptide hormones. In spite of pronounced clinical symptoms, the tumor lesions can be small and difficult to detect. READ MORE

  3. 3. Imaging and Quantification of Brain Serotonergic Activity using PET

    Author : Pinelopi Lundquist; Margareta Hammarlund-Udenaes; Per Hartvig; Gunnar Blomquist; Paul Cumming; Uppsala universitet; []
    Keywords : Pharmacokinetics Pharmacotherapy; Brain serotonin; Neurotransmitter release; Neurotransmitter synthesis; Positron emission tomography; Tracer validation; Tracer modelling; Farmakokinetik Farmakoterapi;

    Abstract : This thesis investigates the potential of using positron emission tomography (PET) to study the biosynthesis and release of serotonin (5HT) at the brain serotonergic neuron. As PET requires probe compounds with specific attributes to enable imaging and quantification of biological processes, emphasis was placed on the evaluation of these attributes. READ MORE