Search for dissertations about: "5s"

Showing result 1 - 5 of 23 swedish dissertations containing the word 5s.

  2. 1. Chromatin remodelling of ribosomal genes - be bewitched by B-WICH

    Author : Anna Vintermist; Ann-Kristin Östlund Farrants; Ross D. Hannan; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chromatin remodelling; ribosomal genes; rDNA; transcription; RNA polymerase I transcription; RNA polymerase III transcription; Cell Biology; cellbiologi;

    Abstract : Transcription of the ribosomal genes accounts for the majority of transcription in the cell due to the constant high demand for ribosomes. The number of proteins synthesized correlates with an effective ribosomal biogenesis, which is regulated by cell growth and proliferation. READ MORE

  4. 2. Regulation of RNA polymerase I and RNA polymerase III transcription by the chromatin remodelling complex B-WICH

    Author : Fatemeh Sadeghifar; Ann-Kristin Östlund Farrants; Magdalena Boguta; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; B-WICH; Chromatin remodelling; ribosomal genes; transcription; Cell Biology; cellbiologi;

    Abstract : Ribosomal biogenesis is an important process which determines the rate of cell growth and is involved in cell response to proliferation, differentiation, cellular nutritional state and stress. The chromatin remodelling complex B-WICH composed of WSTF, SNF2h and NM1 is involved in transcription by the RNA pol I and RNA pol III. READ MORE

  5. 3. Non-protein-coding RNA : Transcription and regulation of ribosomal RNA

    Author : Stefanie Böhm; Ann-Kristin Östlund Farrants; Brian McStay; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ribosomal RNA; non-coding RNA; ribosomal genes; rDNA gene; B-WICH; chromatin remodelling; histone modification; Cell Biology; cellbiologi;

    Abstract : Cell growth and proliferation are processes in the cell that must be tightly regulated. Transcription of ribosomal RNA and ribosomal biogenesis are directly linked to cell growth and proliferation, since the ribosomal RNA encodes for the majority of transcription in a cell and ribosomal biogenesis influences directly the number of proteins that are synthesized. READ MORE

  6. 4. Development of novel therapies for Diamond-Blackfan Anemia

    Author : Shubhranshu Debnath; Hematopoes och genterapi; []
    Keywords : ;

    Abstract : Diamond-Blackfan anemia is a congenital erythroid hypoplasia manifesting early inlife. In at least 60-70% of cases, DBA is caused by a functional haploinsufficiencyof genes encoding for ribosomal proteins. Approximately, 25% percent of patientshave mutations in the gene encoding ribosomal protein S19 (RPS19). READ MORE

  7. 5. Stereoselective synthesis of semiochemicals related to pine sawflies

    Author : Ove Nordin; KTH; []
    Keywords : ;

    Abstract : This thesis describes the stereochemistry and charactericsof (–)-1,6-germacradien-5-ol, isolated from the larvaldefence substance of the pine sawflyNeodiprion sertiferand from the needles of Scots pine,Pinus sylvestris. The conformational behaviour of thissesquiterpene alcohol was investigated by molecular mechanicsstudies (MM2) and NMR. READ MORE