Search for dissertations about: "Aβ42"
Showing result 1 - 5 of 50 swedish dissertations containing the word Aβ42.
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1. Co-assembly of proteins and lipids : From lipodiscs to amyloid aggregates
Abstract : Assemblies of different molecules is a prevalent phenomenon in nature, and crucial in biological life. Most of the biological assemblies are co-assembledcomposites, made up from several different components, either of thesame biomolecular type or a combination of different ones. READ MORE
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2. Amyloid β peptide: from monomer solubility to fibril structure
Abstract : Alzheimer´s disease (AD) is the most common human neuro-degenerative disease characterized by the formation of cerebral plaques. Several are the amyloid-beta (Aβ) variants found in the brain of healthy individuals. READ MORE
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3. Alzheimer disease : a super-resolved picture of the amyloid β-peptide producing machinery
Abstract : Alzheimer disease (AD) is the most common neurodegenerative disease, influencing 40 million patients in the world. Pathologically, AD is hallmarked by intracellular tau tangles and extracellular Amyloid-β peptide (Aβ) plaques. Aβ is generated from the amyloid precursor protein (APP) and its C-terminal fragment (APP-CTF). READ MORE
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4. Alzheimer disease : subcellular Aβ mechanisms and treatment strategies
Abstract : The amyloid β-peptide (Aβ) is the key molecule in the pathogenesis of Alzheimer disease (AD), but the mechanisms of its toxicity are still largely unknown. This thesis includes studies aimed at studying Aβ induced mechanisms in neurons at the subcellular level and explore effective AD treatment strategies. READ MORE
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5. Prediction of Alzheimer’s disease in subjects with Mild Cognitive Impairment using biomarkers
Abstract : Background: Alzheimer’s disease (AD) is the most common cause of dementia. In order to have effect of future disease-modifying therapies for AD, the disease must be identified early, before the patients have developed dementia. Many patients with Mild Cognitive Impairment (MCI) have prodromal AD, but other causes for the syndrome are common. READ MORE