Search for dissertations about: "A E pathogens"

Showing result 1 - 5 of 216 swedish dissertations containing the words A E pathogens.

  1. 1. Origins and Adaptation in Humans : A Case Study of Taste and Lifestyle

    Author : Agnès E. Sjöstrand; Mattias Jakobsson; Evelyne Heyer; Michael G. B. Blum; David Comas; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Evolutionary Genetics; Evolutionär genetik;

    Abstract : In this thesis, I use population genetics and statistical approaches to investigate early human demography, infer local adaptation in diverse sets of populations, and study the genetic basis for taste perception.In the first paper, I examine the genomic evidence for a severe bottleneck, which has been suggested based on paleontological and climate studies to coincide with the emergence of anatomically modern humans. READ MORE

  2. 2. Small Molecules as Tools in Biological Chemistry : Effects of Synthetic and Natural Products on the Type III Secretion System

    Author : Caroline E. Zetterström; Mikael Elofsson; Samuel I. Miller; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type III secretion; salicylidene acylhydrazide; virulence-blocker; virulence; inhibitor; target identification; neohopeaphenol A; Yersinia pseudotuberculosis; Pseudomonas aeruginosa; Escherichia coli; biologisk kemi; biological chemistry;

    Abstract : The increasing use of antibiotics has led to a huge problem for society, as some bacteria have developed resistance towards many of the antibiotics currently available. To help find solutions to this problem we studied small molecules that inhibit bacterial virulence, the ability to cause disease. READ MORE

  3. 3. Population biology of the clonal plant Ranunculus lingua

    Author : Mats E. Johansson; Christer Nilsson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; clonal fragmentation; emergent macrophytes; fungal pathogens; hydrochoiy; invertebrate grazing; marginal population; Peronospora gigantea Prasocuris phellandrt regional abundance; rhizome production; size-number trade-off; vegetative reproduction; water-level fluctuation;

    Abstract : The scope of this thesis was to identify, describe and quantify important life-history traits for the pseudoannual aquatic plant Ranunculus lingua in different ecological settings, by comparing populations from geographically marginal vs. central habitats. READ MORE

  4. 4. Studies of Genome Diversity in Bartonella Populations : A journey through cats, mice, men and lice

    Author : Hillevi Lina Lindroos; Siv G. E. Andersson; Richard Birtles; Uppsala universitet; []
    Keywords : Biology; Bartonella; genome content; genome rearrangement; gene expression; phage; microarray; PFGE; MLST; Biologi;

    Abstract : Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. READ MORE

  5. 5. Type III secretion- the various functions of the translocon operon in bacterial pathogenesis

    Author : Jeanette E Bröms; Åke Forsberg; Michael Koomey; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Yersinia; Pseudomonas aeruginosa; type III secretion; chaperone; translocation; regulation; lcrGVHyopBD; pcrGVHpopBD; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : In order to establish colonisation of a human host, pathogenic Yersinia use a type III protein secretion system to directly intoxicate host immune cells. Activation of this system requires target cell contact and is a highly regulated process. READ MORE