Search for dissertations about: "A GENE PROMOTER"

Showing result 1 - 5 of 606 swedish dissertations containing the words A GENE PROMOTER.

  2. 1. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

    Author : Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. READ MORE

  4. 2. Gene expression in buccal keratinocytes with emphasis on carbonyl metabolism

    Author : Claudia A Staab; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The inner lining of the cheek, the buccal mucosa, is a target for air-borne, dietary and tobacco usage-derived carcinogens, but also interesting from a drug delivery point of view. Cancer arising in the buccal epithelium, buccal squamous cell carcinoma (BSCC), often diagnosed at a late disease stage, is highly aggressive and recurrent, emphasizing the need for novel approaches in diagnosis and therapy. READ MORE

  5. 3. Histone deacetylases and their co-regulators in schizosaccharomyces pombe

    Author : Rebecka A. Silverstein; Karl Ekwall; Anthony Wright; Fred Van Leeuwen; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The DNA in every eukaryotic cell is wrapped around eight core histones to form the nucleosome. Therefore all events that involve DNA must also involve chromatin and nucleosomes. By regulating chromatin structure the cell can regulate the reactivity of the DNA. READ MORE

  6. 4. Exploring the mechanistic details of Gram-positive Type 4 Secretion Systems

    Author : Lena Lassinantti; Ronnie Berntsson; A. Elisabeth Sauer-Eriksson; Sjoerd Wanrooij; Samuel Wagner; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial resistance; Horizontal gene transfer; Gram-positive bacteria; Type 4 Secretion Systems; Conjugation; Enterococcus faecalis; pCF10; PrgU; PcfF; PrgB; Biochemistry; biokemi;

    Abstract : Hospital acquired (i.e. nosocomial) infections and antibiotic resistance are large issues in the world today, with about 1.3 million people estimated to have died from antibiotic resistant infections in 2019 alone, and these problems are on the rise. READ MORE

  7. 5. Promoter Engineering for Cyanobacteria : An Essential Step

    Author : Hsin-Ho Huang; Peter Lindblad; James Golden; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; synthetic biology; cyanobacteria; promoter; engineering; TetR; DNA breathing dynamics; transcription; regulation;

    Abstract : Synthetic biology views a complex biological system as an ensemble in the hierarchy of parts, devices, systems, and networks. The practice of using engineering rules such as decoupling and standardization to understand, predict, and re-build novel biological functions from model-driven designed genetic circuits is emphasized. READ MORE