Search for dissertations about: "A Hober"
Showing result 1 - 5 of 24 swedish dissertations containing the words A Hober.
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1. Strategies for facilitated protein recovery after recombinant production in Escherichia coli
Abstract : The successful genomic era has resulted in a great demand for efficient production and purification of proteins. The main objective of the work described in this thesis was to develop methods to facilitate recovery of target proteins after recombinant production in Escherichia coli. READ MORE
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2. Calcium-dependent Affinity Domains for the Purification of Antibodies and Antibody Fragments
Abstract : Antibodies are essential proteins in both our bodies and biotechnological research, and hold outstanding therapeutic value. The market for antibody-based therapeutics has grown exponentially during the last decades, owing to several advantages over small molecule drugs, such as fewer undesirable side effects associated with a higher target specificity. READ MORE
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3. Engineering of small IgG binding domains for antibody labelling and purification
Abstract : In protein engineering, rational design and selection from combinatorial libraries are methods used to develop proteins with new or improved features. A very important protein for the biological sciences is the antibody that is used as a detecting agent in numerous laboratory assays. READ MORE
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4. An albumin-binding domain as a scaffold for bispecific affinity proteins
Abstract : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. READ MORE
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5. The ADAPT scaffold as a tool for diagnostic imaging and targeted therapy
Abstract : Molecular recognition, or the specific interactions between a protein and its ligand, is central to biology and a key factor for many different clinical and technical applications. Despite antibodies being only one of many different affinity proteins, it has by far been the most successful. READ MORE