Search for dissertations about: "A3"

Showing result 1 - 5 of 45 swedish dissertations containing the word A3.

  2. 1. Equine glutathione transferase A3-3 : an efficient steroid isomerase

    Author : Helena Lindström; Bengt Mannervik; Ann-Kristin Östlund Farrants; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Equine; glutatione transferase; steroidogenesis; steroid isomerase; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication by making toxic electrophiles more polar and therefore more easily excretable. However some GSTs have developed alternative functions. READ MORE

  4. 2. Exploring the steroidogenic activity of glutathione transferases across species

    Author : Helena Lindström; Bengt Mannervik; Kjell Wikvall; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glutathione transferase; steroidogenesis; GST A3-3; testis; androstenedione; pregnenedione; equine; steroidogenesis inhibition; Drosophila GSTE14; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication. However, some GSTs have developed alternative functions. READ MORE

  5. 3. Immunogenetic studies of multiple sclerosis

    Author : Arturs Ligers; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Multiple sclerosis; CTLA-4; HLA-A2; HLA-A3; HLA-DRB1*15; HLA-DRB1*;

    Abstract : Multiple sclerosis (MS) is an inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS). Several genetic factors are likely to be of importance for MS rather than one factor. READ MORE

  6. 4. Molecular dissection of the Goodpasture epitope

    Author : Thomas Hellmark; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urologi; autoimmune; anti-GBM nephritis; glomerulonephritis; nephrology; Urology; nefrologi;

    Abstract : Goodpasture disease is a prototype autoimmune disease that is characterized by a rapidly progressive glomerulonephritis, with or without lung haemorrhage, associated with autoantibodies against the glomerular basement membrane. The major antigen has previously been shown to be the non-collagenous domain of the a3 chain of type IV collagen, one of the six known a chains of type IV collagen. READ MORE

  7. 5. Regulation of site-selective A-to-I RNA editing : During mammalian brain development

    Author : Helene Wahlstedt; Marie Öhman; Mary O'connell; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editering; ADAR; brain development; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Abstract : Adenosine (A) to inosine (I) RNA editing is a widespread post-transcriptional mechanism in mammals that contributes to increase the protein diversity. Adenosine deaminases that act on RNA (ADARs) are the enzymes catalyzing RNA editing. ADARs are particularly active within the brain where they act on transcripts involved in neurotransmission. READ MORE