Search for dissertations about: "ABCB11"
Found 3 swedish dissertations containing the word ABCB11.
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1. ATP-Binding-Cassette Transporters in Biliary Efflux and Drug-Induced Liver Injury
Abstract : Membrane transport proteins are known to influence the absorption, distribution, metabolism, excretion and toxicity (ADMET) of drugs. At the onset of this thesis work, only a few structure-activity models, in general describing P-glycoprotein (Pgp/ABCB1) interactions, were developed using small datasets with little structural diversity. READ MORE
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2. Progressive familial intrahepatic cholestasis : clinical, biochemical, genetic and histopathological aspects
Abstract : In the early 1980's, most cases of neonatal cholestasis (often referred to as neonatal hepatitis) remained unexplained. By today, many of these diseases have been characterized in detail. READ MORE
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3. Intrahepatic cholestasis of pregnancy
Abstract : Intrahepatic cholestasis of pregnancy (ICP) is a condition that has been reported to be associated with an increased fetal risk. A prospective study of ICP was conducted in the Västra Götaland region of Sweden between February 1, 1999 and January 31, 2002. READ MORE