Search for dissertations about: "ACR"

Showing result 1 - 5 of 21 swedish dissertations containing the word ACR.

2. 1. Pharmacometric Modeling in Rheumatoid Arthritis

   Author : Brigitte Lacroix; Lena Friberg; Mats Karlsson; Maria Laura Sargentini-Maier; Kosmas Kretsos; Ekaterina Gibiansky; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; PKPD; immunogenicity; ACR; IPPSE; certolizumab pegol;

   Abstract : Biologic therapies have revolutionized the treatment of rheumatoid arthritis, a common chronic inflammatory disease, mainly characterized by the chronic inflammation of the joints. The activity and progression of the disease are highly variable, both between subjects and between the successive assessments for the same subject. READ MORE

4. 2. Performance of High-temperature Coatings : Oxidation and Interdiffusion

   Author : Xiaoyu Sun; Ru Lin Peng; Johan Moverare; Xin-Hai Li; Lindwall Greta; Linköpings universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; coating; diffusion; phase transformation; oxidation;

   Abstract : The use of aluminiferous coatings profoundly improves the service life of superalloys but leads to the microstructural degradation of superalloys and thus the loss of mechanical properties. To solve this trade-off, two strategies were employed in this research. READ MORE

5. 3. The balance between under- and over-immunosuppression after heart transplantation with emphasis on acute cellular rejection and chronic kidney disease. Experiences from Skåne University Hospital in Lund 1988-2010

   Author : Carl Söderlund; Kardiologi; []
   Keywords : heart transplantation; immunosuppression; acute cellular rejection; chronic kidney disease; generic; heart transplantation; immunosuppression; acute cellular rejection; chronic kidney disase; generic;

   Abstract : Background and aims:Heart transplantation (HT) constitutes the ultimate treatment choice for end-stage heart failure. Following HT, patients require life-long immunosuppressive treatment to prevent allograft rejection. READ MORE

6. 4. Prokaryotic Arsenic Resistance - Studies in Bacillus subtilis

   Author : Emil Aaltonen; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; ArsB; Bacillus subtilis; arsenic resistance; arsenate reduction; arsenite transport; gene regulation; arsenate; ArsR; arsenite; transmembrane topology; Acr3; ArsK;

   Abstract : Arsenic is a toxic metalloid which is found all over the globe. Due to its toxicity and wide abundance, all living organisms have evolved intrinsic arsenic resistance systems. In this study, three proteins that provide arsenic resistance in the Gram-positive bacterium Bacillus subtilis have been investigated. READ MORE

7. 5. Hepatic ischemia-reperfusion injury

   Author : Melroy Alistair D'Souza; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques to reduce blood loss and other intra-operative manoeuvers during liver resection can cause hepatic I/R injury. READ MORE