Search for dissertations about: "AD"

Showing result 11 - 15 of 975 swedish dissertations containing the word AD.

  2. 11. Proximity Ligation Assay for High Performance Protein Analysis in Medicine

    Author : Gucci Jijuan Gu; Ulf Landegren; Thomas Joos; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein; post-translational modification; interactions; protein domain; western blotting; MARK; tau; AD; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Abstract : High quality reagents are preconditions for high performance protein analyses. But despite progress in some techniques, e.g. mass spectrometry, there is still a lack of affinity-based detection techniques with enhanced precision, specificity, and sensitivity. READ MORE

  4. 12. PET and the Multitracer Concept: An Approach to Neuroimaging Pathology

    Author : Henry Engler; Bengt Långström; Göran Hedenstierna; Juha Rinne; Uppsala universitet; []
    Keywords : Neurosciences; PET Positron Emission Tomography ; multitracer; neuroimaging pathology; astrocytes; microglia; neurodegeneration; amyloid; AD; CJD; PD; Neurovetenskap;

    Abstract : Patients suffering from different forms of neurodegenerative diseases, such as: Creutzfeldt Jacob Disease (CJD), Alzheimer disease (AD), mild cognitive impairment (MCI), frontotemporal dementia and Parkinson’s disease (PD) were examined with Positron Emission Tomography (PET) and the combination of different radiotracers: 15O-water, N-[11C-methyl]-L-deuterodeprenyl (DED), [18F] 2-fluorodeoxyglucose: (FDG), N-methyl-[11C]2-(4-methylaminophenyl)-6-hydroxybenzothiazole (PIB) and L-[11C]-3,4-dihydroxiphenyl-alanine (DOPA). The radiotracers and the combinations of different radiotracers were selected with the intention to detect, in the brain, patterns of neuronal dysfunction, astrocytosis, axon degeneration or protein aggregation (amyloid), in the brain which are pathognomonic for specific diseases and may contribute to improve clinical differential diagnoses. READ MORE

  5. 13. Engineering of Affibody molecules targeting the Alzheimer’s-related amyloid β peptide

    Author : Hanna Lindberg; Stefan Ståhl; John Löfblom; Caroline Ekblad; Sara Snogerup Linse; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Affibody molecules; Alzheimer’s disease; AD; amyloid beta; Aß; combinatorial protein engineering; staphylococcal surface display; Bioteknologi; Biotechnology;

    Abstract : .... READ MORE

  6. 14. Radio Network Planning and Resource Optimization : Mathematical Models and Algorithms for UMTS, WLANs, and Ad Hoc Networks

    Author : Iana Siomina; Di Yuan; Peter Värbrand; Arie Koster; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; planning; optimization; wireless networks; radio resources; UMTS; WLAN; ad hoc; Telecommunication; Telekommunikation;

    Abstract : The tremendous popularity of wireless technologies during the last decade has created a considerable expansion of wireless networks both in size and use. This fact, together with a great variety of mobile devices and numerous di®erent services that are becoming increasingly resourcedemanding, have attracted the attention of many researchers into the area of radio resource planning and optimization. READ MORE

  7. 15. Excavating the Digital Landscape : GIS analyses of social relations in central Sweden in the 1st millennium AD

    Author : Daniel Löwenborg; Paul Sinclair; Julian D. Richards; Uppsala universitet; []
    Keywords : HUMANIORA; HUMANITIES; landscape archaeology; GIS; Iron Age; Västmanland; burial grounds; Vendel Period; Viking Age; territorial organisation; watersheds; statistical analysis; chronology; discriminant analysis; GWR; spatial analysis; perception; topography; AD 536; Fimbulvinter; property rights; crisis; historical ecology.; Archaeology; Arkeologi; Archaeology; Arkeologi;

    Abstract : This thesis presents a number of GIS based landscape analyses that together aim to explore aspects of the social development in Iron Age Västmanland, central Sweden. From a perspective where nature and culture are seen as integrated in the landscape, differences in the relations to the physical landscape are interpreted as reflecting social organisation. READ MORE