Search for dissertations about: "ADFP"

Found 2 swedish dissertations containing the word ADFP.

  2. 1. The assembly of cytosolic lipid droplets and its effect on insulin sensitivity

    Author : Pontus Boström; Göteborgs universitet; []
    Keywords : diabetes; lipid metabolism; insulin resistance; lipid droplets; ADFP; SNARE;

    Abstract : Accumulation of neutral lipids, in particular triglycerides, in non-adipocytes is highly related to the development of insulin resistance and its consequences, type-2 diabetes and cardiovascular diseases. The accumulation of triglycerides occurs in so-called lipid droplets in the cytosol. READ MORE

  4. 2. LXR regulation of hepatic gene expression and pituitary dependent hormones

    Author : Pia Kotokorpi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Liver X receptor; growth hormone; gene regulation; metabolism; hepatocyte; hepatic steatosis; species differences;

    Abstract : The liver X receptors (LXRs) are ligand activated transcription factors involved in the regulation of metabolic genes. LXRs are considered potential drug targets to treat metabolic disorders, however, unwanted side effects, as revealed from rodent studies, include increased lipogenesis in the liver and increased plasma triglyceride levels. READ MORE