Search for dissertations about: "ADH1"

Showing result 1 - 5 of 15 swedish dissertations containing the word ADH1.

2. 1. Improving the Response of Saccharomyces cerevisiae to Lignocellulosic Hydrolysate Inhibitors in Ethanolic Fermentation

   Author : Joao Almeida; Teknisk mikrobiologi; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; furfural; ethanol; fermentation; phenolics; furaldehyde; HMF; ADH1; xylose reductase; tolerance; Saccharomyces cerevisiae; Lignocellulosic hydrolysate inhibitors; ADH6;

   Abstract : The production of ethanol based on lignocellulosic biomass requires the fermentation of a hydrolysate containing hexose and pentose sugars in an inhibitory environment. In fact, the lignocellulosic hydrolysate obtained from pretreatment and hydrolysis of the raw material contains a variety of inhibitory compounds, including (i) the furaldehydes 5-hydroxymethyl-2-furaldehyde (HMF) and 2-furaldehyde (furfural), (ii) weak acids (e. READ MORE

4. 2. Genes involved in Parkinson's disease : focus on mitochondrial and detoxifying enzymes

   Author : Anna Anvret; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Parkinson's disease is a common progressive neurodegenerative disorder which mostly affects the elderly population, with a prevalence of more than 1.5% in the population over the age of 65 years. Clinical motor symptoms are mainly caused by degeneration of dopamine neurons in substantia nigra pars compacta. READ MORE

5. 3. Cytokines, alcohol metabolizing enzymes and stress-inducible ER proteins in alcoholic liver disease

   Author : Che Fang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The release of inflammatory cytokines by Kupffer cells is believed to be a key step in the pathogenesis of alcoholic liver disease (ALD). Kupffer cells are activated not only by endotoxins [lipopolysaccharides (LPS)] but also by the lipid peroxidation products generated mainly via ethanol-inducible cytochrome P450 2E1 (CYP2E1) redox cycling. READ MORE

6. 4. Structural and mechanistic aspects of alcohol dehydrogenase function

   Author : Stefan Svensson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Vertebrates possess a complex alcohol dehydrogenase (ADH) system composed of multiple molecular forms, which are currently classified into seven classes according to their structural properties. ADHs are dimeric zinc metalloenzymes that catalyze the reversible oxidation of alcohols to aldehydes/ketones using NAD+/NADH as electron acceptor and donor, respectively. READ MORE

7. 5. Genetic Traits Beneficial for Xylose Utilization by Recombinant Saccharomyces cerevisiae

   Author : Oskar Bengtsson; Teknisk mikrobiologi; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Saccharomyces cerevisiae; metabolic engineering; fermentation; xylose; ethanol; promoter; xylose reductase; cofactor; validation; transcriptome;

   Abstract : Saccharomyces cerevisiae ferments hexoses in lignocellulosic hydrolysates under anaerobic conditions with high rates and ethanol yields. However, S. cerevisiae is naturally unable to utilize the pentose fraction of the hydrolysates. Xylose is the most abundant pentose sugar, and although recombinant S. READ MORE