Search for dissertations about: "AHR"

Showing result 6 - 10 of 73 swedish dissertations containing the word AHR.

  2. 6. Signaling via the bHLH-PAS proteins AhR and HIF

    Author : Cecilia Bosdotter; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis concerns some mechanistic properties of the basic helix-loop-helix/PAS (bHLH-PAS) factors aryl hydrocarbon receptor (AhR) and hypoxia-inducible factor 1 alpha (HIF-1α). The bHLH-PAS family of proteins is a family of factors that controls a variety of developmental and physiological events. READ MORE

  4. 7. From Proteomic Analysis to Biomarker Application - Studies of Carbonyl Reductase in Fish

    Author : Eva Albertsson; Göteborgs universitet; []
    Keywords : Fish; Proteomics; Biomarker; Carbonyl Reductase; AhR agonists; Oxidative stress; Biomonitoring;

    Abstract : Many anthropogenic substances are present in the aquatic environment, but there is limited information on how this combination of chemicals affects exposed wildlife. To assess the impact of chemicals, a biomarker approach is frequently applied in environmental biomonitoring programmes. READ MORE

  5. 8. Change of toxicity during secondary treatment of industrial sludge containing nitroaromatics

    Author : Lillemor Gustavsson; Magnus Engwall; Anna Schnürer; Ulrika Welander; Mårten Jönsson; Bo Mattiasson; Göran Dave; Örebro universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Anaerobic; aerobic; AhR agonists; CALUX; constructed wetlands; Danio rerio; embryotoxicity; genotoxicity; nitroaromatics; sludge; Environmental engineering; Miljöteknik; Enviromental Science; Miljövetenskap;

    Abstract : Wastewater treatment plants in Sweden are facing a great challenge due to the prohibition of depositing organic waste which gained legal force in January 2005. Biological and commercial available alternatives to disposal are composting and anaerobic digestion. READ MORE

  6. 9. Identification of novel pathways of regulation of AHR and HIF-­1 function

    Author : Michael Gralla; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mammalian bHLH-Pas (basic HLH (helix-loop-helix)-PER-ARNT-SIM) proteins belong to the bHLH superfamily of transcription factors. Members of the family have a broad spectrum of functions that among others sense and regulate the cellular response to physiological signals such as low oxygen levels (hypoxia), or environmental signals such as toxins. READ MORE

  7. 10. The microbiome, PPARγ and AhR in the inflammation-metabolism interface within the gastrointestinal tract

    Author : Agata Korecka; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The mammalian body is a mosaic of different organisms - a holobiont, which contains all the biomolecules and their metabolites encoded in our eukaryotic genome and supplemented by an even larger pool of prokaryotic genes and products. This symbiotic coexistence is presumed to have evolved to necessitate the sharing of biological and biochemical needs important for growth, body physiology, survival and reproduction. READ MORE