Search for dissertations about: "ALDH"
Showing result 1 - 5 of 8 swedish dissertations containing the word ALDH.
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1. Hypoxia and Stem Cells in Normal and Tumor Development
Abstract : Neuroblastoma is a childhood malignancy of the sympathetic nervous system and accounts for 15% of all cancer-related deaths in children. To understand the biology behind neuroblastoma, clarify timing of cellular events and expression profiles of proteins preceding neuroblastoma initiation, we need more relevant preclinical models. READ MORE
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2. Exploring the heterogeneity of the hematopoietic stem and progenitor cell pool in cord blood
Abstract : Hematopoietic stem cell transplantation (HSCT) is a curative treatment for a wide range of malignant and hereditary disorders. It is yet the only clinically established stem cell treatment. READ MORE
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3. The Role of Inflammatory Lipid Mediators on Colon Cancer Initiating Cells (CICs)
Abstract : Colorectal cancer (CRC) is one of the major causes of cancer globally. Recent studies proposed a role for cancer initiating cells (CICs), a small subset of replication-competent cells, in colon carcinogenesis. READ MORE
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4. Medium chain dehydrogenases/reductases : alcohol dehydrogenases of novel types
Abstract : The medium chain dehydrogenase/reductase (MDR) superfamily is separated into at least eight families, of which the dimeric alcohol dehydrogenase (ADH) is one. Including species variants, close to 1000 MDR forms have been characterized. READ MORE
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5. Regulation of normal and cancer cells as a base for cell cycle-targeted therapy
Abstract : The majority of current treatments used for treatment of prostate cancer (PCa) and leukemia are often limited to a narrow subsets of treated patients. As such, there still remains a significant scope for gaining deeper understanding of molecular mechanisms underlying cancer metastasis for improvement of targeted treatment. READ MORE