Search for dissertations about: "AMP-activated protein kinase AMPK"
Showing result 1 - 5 of 20 swedish dissertations containing the words AMP-activated protein kinase AMPK.
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1. AMP-activated protein kinase in adipose tissue
Abstract : The AMP-activated protein kinase (AMPK) is a ubiquitously expressed kinase, which is activated in response to depletion of cellularenergy levels. Once active, it functions to alter cellular metabolism in a way that leads to restoration of energy levels. Therefore,AMPK is described as the key regulator of cellular energy homeostasis. READ MORE
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2. AMP-activated protein kinase : the connection between exercise and type II diabetes
Abstract : Skeletal muscle insulin resistance is a hallmark feature of Type 2 diabetes. Physical exercise/muscle contraction elicits an insulin-independent increase in glucose transport and perturbation of this pathway can bypass defective insulin signaling. READ MORE
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3. Skeletal muscle metabolic flexibility : the roles of AMP-activated protein kinase and calcineurin
Abstract : Skeletal muscle fibers differ considerably in their metabolic and physiological properties. The metabolic properties of skeletal muscle display a high degree of flexibility which adapts to various physiological demands by shifting energy substrate metabolism. READ MORE
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4. Protein kinases in hormonal regulation of adipocyte metabolism
Abstract : Abstract Along with liver and muscle tissue, adipose tissue helps maintain normal levels of glucose and lipids in the blood and has a very important role when it comes to storing lipids that can provide whole-body energy. After a meal is ingested, adipocytes take up glucose from the circulation and use it as a substrate for synthesis of new fatty acids (FAs) in a process known as de novo fatty acid synthesis, as well as for synthesis of glycerol. READ MORE
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5. Global Regulation of Snf1 in Saccharomyces cerevisiae: A case study of experimental systems biology
Abstract : Cells commonly face environmental changes and have evolved various regulatory mechanisms to adjust their metabolism accordingly. One such key regulator in S. cerevisiae is the Snf1 kinase, which belongs to the conserved AMP-activated protein kinase (AMPK) family in all eukaryotes. READ MORE