Search for dissertations about: "AMPs"

Showing result 16 - 20 of 56 swedish dissertations containing the word AMPs.

  2. 16. Polymeric Nanoparticles as Carriers for Antimicrobial Peptides : Factors Affecting Peptide and Membrane Interactions

    Author : Randi Nordström; Martin Malmsten; Per Hansson; Helena Bysell; Erica Wanless; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antimicrobial peptide; microgel; degradable; nanogel; drug delivery; PEGylation; secondary structure; model membrane; lipid bilayer; neutron reflectometry; ellipsometry; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Abstract : As resistance towards conventional antibiotics is becoming more pronounced, cationic antimicrobial peptides (AMPs) have received considerable attention as possible therapeutic alternatives. Thousands of potent AMPs occur in humans, animals, plants and fungi as a natural part of the immune system. READ MORE

  4. 17. STRUCTURAL, FUNCTIONAL AND EVOLUTIONARY STUDIES OF ANTIMICROBIAL PEPTIDES

    Author : Mukesh Pasupuleti; Lund Dermatologi och venereologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amphipathicity and end-tagging protease susceptibility; anaphylatoxin C3a; P. aeruginosa; S. aureus; innate immunity; amphipathic molecules; Antimicrobial peptides; infectious disease; bacteriostatic; microbicidal and cytolytic properties;

    Abstract : Antimicrobial peptides represent a heterogeneous group that displays multiple modes of action such as bacteriostatic, microbicidal and cytolytic properties that are sequence and concentration dependent. Life threatening infectious disease is now a worldwide crisis and treating them effectively is becoming difficult day by day, due to the emergence of antibiotic resistant strains at alarming rates. READ MORE

  5. 18. Development of lipodisks as carriers for cationic amphiphilic peptides

    Author : Karin Reijmar Brunnström; Katarina Edwards; Fredrik Höök; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Antibiotics have made a tremendous contribution to mankind. They are one of the most successful medicines in human history. However, more and more bacterial strains develop resistance and the risk to public health can hardly be overstated. New types of antibiotics are urgently needed. READ MORE

  6. 19. Measuring quality of occupational performance based on self-report and observation : development and validation of instruments to evaluate ADL task performance

    Author : Eva Ejlersen Waehrens; Anne G Fisher; Hans Lund; Bente Danneskiold-Samsöe; Lena von Koch; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; activities of daily living; acquired brain injury; ADL evaluation; ADL task performance; chronic disease; chronic widespread pain; interview; observation; occupational therapy; observation-based evaluation; questionnaire; Rasch measurement; rheumatic diseases; Occupational therapy; Arbetsterapi; Occupational therapy; arbetsterapi;

    Abstract : Background People with rheumatic or neurologic conditions are commonly referred for occupational therapy because of decreased ability to perform ADL tasks. Upon referral, occupational therapists use a client-centred, occupationfocused approach when evaluating a person's perceived and observed quality of ADL task performance to clarify the nature and extent of the person’s problems, plan interventions and determine effectiveness of interventions. READ MORE

  7. 20. Antibacterial materials for wound care applications utilizing antimicrobial peptides

    Author : Edvin Blomstrand; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; self-assembly; lyotropic liquid crystals; antibacterial surface; Antimicrobial peptides; Pluronic F-127; hydrogels;

    Abstract : The spread of antibiotic resistance among bacteria has shown that the development of alternative treatments of infections is of vital importance. This thesis has looked at one potential candidate, antimicrobial peptides (AMPs), as an alternative or compliment to traditional antibiotics. READ MORE