Search for dissertations about: "AMPs"

Showing result 6 - 10 of 56 swedish dissertations containing the word AMPs.

  1. 6. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    Author : Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

    Abstract : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. READ MORE

  2. 7. Antimicrobial peptides and proteins in host-microbe interaction and immediate defense

    Author : Ylva Kai-Larsen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antimicrobial peptides and proteins (AMPs) are effector molecules of innate immunity and are capable to kill a broad spectrum of microbes, i.e. bacteria, fungi and viruses. They are widespread in nature and have been found in almost all species of the animal kingdom, as well as in plants. READ MORE

  3. 8. Midkine - a host defence protein

    Author : Sara Nordin; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antimicrobial polypeptides; Midkine; antibacterial; antifungal; innate immunity; epithelial surfaces;

    Abstract : Every day we encounter many potentially harmful microbes in our environment. The epithelial linings constitute an anatomical barrier protecting us and they also produce antimicrobial polypeptides (AMPs) that act as a chemical barrier. These AMPs are small and positively charged, killing a broad range of microbes rapidly. READ MORE

  4. 9. Occupation-based evaluation and intervention : validity of the assessment of motor and process skills when used with persons with mental retardation

    Author : Anders Kottorp; Birgitta Bernspång; Anne G. Fisher; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mental retardation; intellectual disability; developmental disabilities; occupational therapy; activities of daily living; ADL assessment; performance skills; occupational performance; Many- faceted Rasch measurement; single case design;

    Abstract : The ability to perform everyday life occupations is a critical component in both evaluation and intervention for persons with mental retardation (MR). While the ability to perform personal and instrumental activities of daily living (ADL) has always been important for occupational therapy (OT) practice, there is an absence in OT literature and research with a focus on ADL and persons with MR. READ MORE

  5. 10. Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides

    Author : Hava Lofton Tomenius; Dan I Andersson; Ørjan Samuelsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial peptides; antibiotic resistance; fitness cost; Salmonella Typhimurium; Staphylococcus aureus; bile; serum; pH response; growth rate; mice; phoP; pmrB; waaY; LPS; LL-37; defensins; membrane potential; Mikrobiologi; Microbiology;

    Abstract : The global increasing problem of antibiotic resistance necessarily drives the pursuit and discovery of new antimicrobial agents. Antimicrobial peptides (AMPs) initially seemed like promising new drug candidates. Already members of the innate immune system, it was assumed that they would be bioactive and non-toxic. READ MORE