Search for dissertations about: "ANCA vasculitis"

Showing result 1 - 5 of 20 swedish dissertations containing the words ANCA vasculitis.

  1. 1. Clinical and epidemiological Studies in ANCA-associated vasculitis

    Author : Jens Rathmann; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vasculitis; ANCA vasculitis; Epidemiologi; Infection; Classification;

    Abstract : Objectives:This thesis aims to provide an overview of the epidemiology of AAV in southern Sweden, to evaluate different classification criteria in AAV. In addition we study if infection is a risk factor for later development of AAV comparing patients with AAV with a matched population cohort and to examine the occurrence of severe infections as an outcome in AAV. READ MORE

  2. 2. The Balance between Pro- and Antiinflammatory Molecules in ANCA-Associated Vasculitis

    Author : Sophie Ohlsson; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nephrology; Urologi; nefrologi; Urology; monocyte; SLPI; proteinase 3; ANCA; vasculitis; inflammation;

    Abstract : ANCA-associated systemic vasculitis (AASV) is a group of inflammatory disorders, characterized by inflammation and necrosis of blood vessels and frequently granuloma formation. Patients with AASV make autoantibodies, so called ANCA, against proteins present in the granules of neutrophils and monocytes, mainly proteinase 3 (PR3) and myeloperoxidase (MPO). READ MORE

  3. 3. Studies on the Epidemiology and Outcome of Primary Systemic Vasculitis

    Author : Aladdin Mohammad; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polyarteritis nodosa; survival; microscopic polyangiitis; arteritis; vasculitis damage index; Vasculitis; ANCA; Wegener s granulomatosis; Churg-Strauss syndrome;

    Abstract : Primary Systemic Vasculitides [PSV: Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS) and polyarteritis nodosa (PAN)] are rare systemic diseases of unknown etiology; if untreated, they are associated with high morbidity and mortality rates. Changes in the classification and diagnostic improvements during the last decades have increased reported prevalence and incidence rates of PSV. READ MORE

  4. 4. Autoimmunity in glomerulonephritis; serological diagnosis and clinical outcome with special reference to Wegener´s granulomatosis and microscopic polyangiitis

    Author : Kerstin Westman; Njurmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener´s granulomatosis; vasculitis; thyroid peroxidase antibodies; proteinase 3; myeloperoxidase; antineutrophil cytoplasmic antibodies; ANCA; thyroiditis; autoantibodies; glomerulonephritis; microscopic polyangiitis; Urology; nephrology; Urologi; nefrologi;

    Abstract : Autoantibodies of different specificites have been described in association with glomerulonephritis and therefore the aim of this thesis was to improve our knowledge of the different manifestations of autoimmune phenomena which are involved in the glomerulonephritides. Special reference is made to Wegener´s granulomatosis (WG) and microscopic polyangiitis (MP) which are frequently associated with the prevalence of anti-neutrophil cytoplasmic antibodies (ANCA). READ MORE

  5. 5. Long-term follow-up of patients with ANCA-associated vasculitis

    Author : Caroline Heijl; Njurmedicin; []
    Keywords : Anca-associated vasculitis;

    Abstract : This thesis is based on long-term follow-up results from two cohorts of patients with ANCA-associated vasculitis; one cohort with 535 patients originally included in 4 European randomized clinical trials (papers I and II) and one Swedish population-based cohort including 195 patients (papers III and IV). Two areas are covered in the two cohorts, respectively; the assessment of mortality, prognostic factors and causes of death in the two cohorts (paper I and III) and the assessment of malignancy risk compared with a matched general population (papers II and IV). READ MORE