Search for dissertations about: "ANGIOGENESIS REPRODUCTIVE"

Showing result 1 - 5 of 19 swedish dissertations containing the words ANGIOGENESIS REPRODUCTIVE.

  2. 1. The Human Endometrium : Studies on Angiogenesis and Endometriosis

    Author : Christian Moberg; Matts Olovsson; Anneli Stavreus-Evers; Lalit Kumar Parameswaran Grace; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endometrium; angiogenesis; endothelial cell; endometriosis; receptivity; implantation; oestrogen receptor; progesterone receptor; crystallin; interleukin; vasoactive intestinal peptide; peritoneal fluid; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Angiogenesis is thought to play a pivotal role in the cycling endometrium. Coordinated by oestrogen and progesterone, endometrial blood vessel development is primarily mediated by vascular endothelial growth factor-A (VEGF-A), which promotes endothelial cell (EC) proliferation and protects ECs from induced apoptosis. READ MORE

  4. 2. Oxidative Stress, Angiogenesis and Inflammation in Normal Pregnancy and Postpartum

    Author : Maria Palm; Ove Axelsson; Samar Basu; Charlotta Grunewald; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; inflammation; IL-6; F2-isoprostanes; oxidative stress; Pentraxin 3; PGF2α; PlGF; pregnancy; sFlt1; TNF-α; VEGF-A; Obstetrik och gynekologi; Obstetrics and Gynaecology; Medicinsk vetenskap; Medical Science;

    Abstract : The aims were to investigate oxidative stress (I), angiogenesis (II) and inflammation (III-IV) in healthy women during pregnancy and postpartum. Oxidative stress was estimated by measurement of 8-iso-PGF2α and the antioxidants α- and γ-tocopherol. READ MORE

  5. 3. Biological Markers of Fertility

    Author : Sarah Nordqvist; Helena Åkerud; Karin Kårehed; Agneta Skoog Svanberg; Anneli Stavreus-Evers; Geraldine Hartshorne; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; embryogenesis; female reproductive tract; fertility; fertilization; Histidine-rich glycoprotein; intron; in vitro fertilization; oocyte; ovarian response; pregnancy; single nucleotide polymorphism; Src homology 2 domain-containing adapter protein B;

    Abstract : Infertility affects 15 % of couples, which corresponds to 60 - 80 million worldwide. The microenvironments in which the oocyte, embryo and fetus mature are vital to the establishment and development of a healthy pregnancy. READ MORE

  6. 4. Growth factor regulation of the urokinase plasminogen activator (uPA) system in human endometrium, and the significance of uPA receptor activation in endometrial angiogenesis

    Author : Tove Sandberg; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; endothelial cell migration; angiogenesis; uPA:PAI-1 complex; uPAR; TGF-beta; PAI-1; EGF; uPA; Growth factor; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : The purpose of this thesis was to examine the role of growth factors and the urokinase plasminogen activator (uPA) system in human endometrial angiogenesis. Growth factors as well as progesterone increased expression of the main inhibitor of uPA (PAI-1) in primary cultures of endometrial stromal cells. READ MORE

  7. 5. Effects of Endocrine Disrupting Chemicals on Human Endometrial Endothelial Cells In Vitro

    Author : Malin Helmestam; Matts Olovsson; Anneli Stavreus-Evers; Yvonne Lundberg Giwercman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endocrine disrupting chemicals; hormones; human endometrial endothelial cells; endometrium; estrogen; progesterone; cadmium; tamoxifen; mifepristone; bisphenol A; angiogenesis; Medicinsk vetenskap; Medical Science;

    Abstract : Evidence from an abundant number of studies suggests that human female reproductive functions have become impaired over the past half century and that there might be a relationship between endocrine disrupting chemicals (EDCs) and reduced fertility. It is, however, not known by what mechanisms EDCs affect different reproductive functions such as endometrial receptivity, embryo implantation and placentation. READ MORE