Search for dissertations about: "ARBs"
Showing result 1 - 5 of 7 swedish dissertations containing the word ARBs.
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1. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure
Abstract : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. READ MORE
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2. Epidemiological studies on socioeconomic inequalities and cardiovascular disease : prevention, progression and prognosis
Abstract : Cardiovascular disease (CVD) accounts for 30% of global mortality and is the most common cause of death in the world. Population-wide prevention strategies as well as healthcare interventions have led to a decrease in CVD incidence and mortality. READ MORE
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3. Angiotensin II Receptors in the Human Coronary Circulation and in Heart Failure
Abstract : Angiotensin II (Ang II) is a potent vasoconstrictor that is implicated in the pathogenesis of hypertension, heart failure and atherosclerosis. In this thesis, the efficacy and safety of Ang II receptor blockers (ARB) were evaluated. READ MORE
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4. Membranous Nephropathy - Challenges in diagnostics and treatment
Abstract : The variability in the pathogenesis, clinical presentation and outcome of membranous nephropathy (MN) poses major clinical challenges and raises different questions, both regarding diagnostics and treatment of patients with MN. The aims of this thesis were therefore to examine: 1) differences in the glomerular expression of different IgG subclasses and phospholipase A2 receptor (PLA2R) between patients with idiopathic and malignancy-associated MN; 2) treatment pattern of patients with idiopathic MN; and 3) if the serum PLA2R antibody level at diagnosis can be used as a prognostic marker. READ MORE
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5. Mineralocorticoid receptor antagonists in heart failure : exploring the gap between guideline-directed medical therapy and real-world practice
Abstract : Heart failure is the possible end-result of a variety of different diseases, where ischemic heart disease and hypertension are the most common causes in high income countries. In Sweden, heart failure has a prevalence of 2% in the adult population and rises to over 10% among people over 70 years of age. The 5-year all-cause mortality is about 50%. READ MORE