Search for dissertations about: "ARDS"

Showing result 1 - 5 of 36 swedish dissertations containing the word ARDS.

  1. 1. Aspects on ventilation induced stress and strain on regional and global inflammation in experimental acute respiratory distress syndrome

    Author : Jaime Retamal Montes; Anders Larsson; Göran Hedenstierna; Alejandro Bruhn; Björn Jonson; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ARDS; VILI; respiratory rate; strain; PET;

    Abstract : Mechanical ventilation (MV) is a life-saving therapy in acute respiratory distress syndrome (ARDS), a condition that affects 3000 patients/year in Sweden with a mortality rate of about 40%. However, MV may induce or worsen lung injury causing “ventilator-induced lung injury (VILI)”. READ MORE

  2. 2. Monitoring alveolar recruitment in the critically ill - Patient studies using electric impedance tomography and volume-dependent compliance

    Author : Karin Lowhagen; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALI; ARDS; compliance; end-expiratory lung volume; EELV; EIT; electric impedance tomography; lung recruitment; morbid obesity; PEEP; recruitment manoeuvre; regional ventilation; volume-dependent compliance;

    Abstract : Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are associated with a high mortality rate and poor long term outcome in terms of quality of life, for those who survive. Similarly, patients with morbid obesity are at risk for respiratory complications when subjected to anaesthesia and surgery. READ MORE

  3. 3. Function of granulocytes after burns and trauma, associations with pulmonary vascular permeability, acute respiratory distress syndrome, and immunomodulation

    Author : Joakim Johansson; Folke Sjöberg; Lennart Lindbom; Sven-Erik Ricksten; Linköpings universitet; []
    Keywords : ARDS; azurocidin; burn; CAP-37; critical care; granulocyte; HBP; histamine; intensive care; leucocyte; leukocyte; mediator; methylhistamine; MOF; oedema; neutrophil; permeability; PMN; trauma; vascular permeability;

    Abstract : Background: Our innate immunesystem protects us from infections but, since its methods is not all specific for microorganisms, may also induce collateral damage.Severe physical injury often proved deadly throughout evolution. Such injuries may induce massive collateral damage. READ MORE

  4. 4. Titrating Open Lung PEEP in Acute Lung Injury : A clinical method based on changes in dynamic compliance

    Author : Fernando Suarez Sipmann; Göran Hedenstierna; Hans Hedenström; Stefan Lundin; Uppsala universitet; []
    Keywords : AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; PEEP; open lung; recruitment; dead space; electrical impedance tomography; ARDS.; Medicine; Medicin;

    Abstract : The recognition that supportive mechanical ventilation can also damage the lung, the so called ventilation induced lung injury (VILI), has revived the more than 40 year long debate on the optimal level of PEEP to be used. It is established that the prevention of VILI improves patient outcome and that PEEP exerts protective effects by preventing unstable diseased alveoli from collapsing. READ MORE

  5. 5. A Surface Phase Model of the Alveolar Lining: Ultrastructural Analysis and in vivo Applications

    Author : Marcus Larsson; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; X-ray diffraction; cryo-TEM; dynamic swelling; ARDS; surface phase; surfactant replacement therapy; cholesterol; minimal surface; pulmonary surfactant; alveolar surface; Physiology; Fysiologi;

    Abstract : In this thesis the relation between lung surfactant structure and functional properties have been studied. Experimental results show that the alveolar surface is formed by a coherent surface phase with a structure equal to tubular myelin. The properties of this phase may explain certain unresolved issues in lung physiology, e.g. READ MORE