Search for dissertations about: "ARG"

Showing result 1 - 5 of 90 swedish dissertations containing the word ARG.

  1. 1. Structural and synthetic studies on peptide analogues to the cell adhesive sequence RGD (Arg-Gly-Asp)

    Author : Henrik Mickos; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Fibronectin is a cell adhesive protein with many different biological functions. The cell adhesive properties have been ascribed on a small polypeptide sequence RGD (Arginine-Glycine-Aspartic acid) also found in other cell adhesive proteins. READ MORE

  2. 2. Pro- and anticoagulant activities of factor V

    Author : Elisabeth Thorelli; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; activated protein C; protein S; factor VIII; factor V; procoagulant; anticoagulant; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : Coagulation factor V (FV) is activated by thrombin through proteolytic cleavage at Arg-709, Arg-1018 and Arg-1545. Upon thrombin activation, the active form of factor V (FVa) is formed. FVa functions as a cofactor to factor Xa in the conversion of prothrombin to thrombin during coagulation. READ MORE

  3. 3. Bioactive adsorbates on gold surfaces : structural properties and bio-interaction studies

    Author : Rodrigo Jr Petoral; Hans Siegbahn; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : This thesis investigates the properties of biomolecular, model adsorbates on gold such as amino acid derivatives, peptides and related organic molecules. Subsequent bin-interaction studies were also conducted. READ MORE

  4. 4. Expanding the Amino Acid Alphabet by Design : Enhanced and Controlled Catalytic Activity in Folded Polypeptide Catalysts

    Author : N. Johan V. Lindgren; Lars Baltzer; Harri Lönnberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemistry; Kemi; Organic Chemistry; organisk kemi;

    Abstract : This thesis addresses structure and reactivity of polypeptide catalysts in reactions that mimic the hydrolysis of RNA and DNA. A designed helix-loop-helix motif was used as a scaffold where the amino acid residues were systematically varied. READ MORE

  5. 5. Studies on vasoactivity of fibrin(ogen) derived peptides

    Author : Katarina Saldeen; Asrar Malik; Linköpings universitet; []
    Keywords : Fibrin ogen derived peptides; vasoactivity; prostacyclin; nitric oxide; angiotensin converting enzyme; MEDICINE; MEDICIN;

    Abstract : Fibrin accumulation is a common fmding in many pathological conditions, such as in inflammatory processes, e.g. in the lungs in pneumonia or pulmonary insufficiency after sepsis. During lysis of the fibrin by plasmin or leukocyte elastase, peptides are released that may contribute to the pathophysiological changes. READ MORE