Search for dissertations about: "ASP .NET"

Showing result 11 - 15 of 35 swedish dissertations containing the words ASP .NET.

  2. 11. Fighting isoaspartate

    Author : Jijing Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Isoaspartate (IsoAsp) is a damaging amino acid residue generated either from asparagine (Asn) deamidation or aspartate (Asp) isomerization. Both reactions are spontaneous in physiological conditions and require no enzymes. In isoAsp, a CH2 group is rearranged from the side chain and extends the polypeptide backbone. READ MORE

  4. 12. Regulation of tartrate-resistant purple acid phosphatase by proteolytic processing in rat

    Author : Jenny Ljusberg-Sjölander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Purple acid phosphatase; enzyme catalysis; proteolytic processing;

    Abstract : Purple acid phosphatase (PAP) is an iron-containing binuclear acid metallohydrolase with a characteristic purple colour, also referred to as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase. PAP is highly expressed in osteoclasts and has a role in bone resorption. READ MORE

  5. 13. Leukotriene A4 hydrolase : studies of structure-function relationships by site-directed mutagenesis and X-ray crystallography

    Author : Peter C Rudberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Inflammation is the pathophysiological mechanism by which an organism clears and rebuilds a site of infection or injury. It is also the characteristic feature of a multitude of severe diseases, with the potential of afflicting almost any organ system. READ MORE

  6. 14. Modeling human germ cell development with pluripotent stem cells and characterizing the putative oogonial stem cells

    Author : Sarita Panula; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The current understanding of human germ cell development is limited and is at most parts extrapolated from studies of mice or other model organisms. Particularly, the specification events of human germ cell lineage are largely unknown, which is at least in part due to inaccessibility of early stages of human development. READ MORE

  7. 15. Spinal cord stimulation in neuropathy : experimental studies of biochemistry and behaviour

    Author : Jian-Guo Cui; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neuropathic pain; mononeuropathy; GABA; glutamate; aspartate; galanin; neuropeptide Y; adenosine; spinal cord stimulation;

    Abstract : Neuropathic pain, presenting with cutaneous hypersensitivity, i.e. allodynia, dysesthesia and hyperalgesia, is often difficult to manage with pharmacotherapy, but may be effectively alleviated by electric spinal cord stimulation (SCS). However, the mode of action of SCS is still poorly understood. READ MORE