Search for dissertations about: "AST ALT ratio"

Showing result 6 - 8 of 8 swedish dissertations containing the words AST ALT ratio.

  1. 6. Mechanistic studies of APR-246 in leukemia

    Author : Dina Mahmoud Ali; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : PRIMA-1 and its analog APR-246 are novel drugs that restore the active conformation of mutated and unfolded p53 protein and induce apoptosis and cell death in various tumors in pre-clinical models. We first aimed to explore the effects of APR-246 alone and in combination with other drugs in acute myeloid leukemia (AML) in vitro. READ MORE

  2. 7. Evaluation and clinical application of ethyl glucuronide and ethyl sulfate as biomarkers for recent alcohol consumption

    Author : Helen Dahl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In recent years, there has been a growing interest in various biochemical markers for detecting acute and chronic alcohol consumption. Biochemical markers for acute and chronic drinking play important roles in detecting alcohol use, abuse and dependence in hospital settings, work place settings, traffic medicine and in forensic toxicology examinations. READ MORE

  3. 8. Hyperinflammation in critically ill

    Author : Tatiana von Bahr Greenwood; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: A wide spectrum of inflammatory responses, with overlapping characteristics, is encountered in critically ill patients in intensive care. At one extreme, critically ill patients may develop the potentially fatal condition secondary hemophagocytic lymphohistiocytosis (sHLH), characterized by excessive inflammation (hyperinflammation), driven by a ‘cytokine storm’, and multiple organ failure. READ MORE